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10.18632/aging.103941 http://scihub22266oqcxt.onion/10.18632/aging.103941 33065551!7655207!33065551     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Aging+(Albany+NY) 2020 ; 12 (20): 19867-19879 Nephropedia Template TP {{tp|p=33065551|t=2020. CD45: a critical regulator in immune cells to predict severe and non-severe COVID-19 patients |pdf=|usr=}}{{33065551}} gab.com Text CD45: a critical regulator in immune cells to predict severe and non-severe COVID-19 patients JO: Aging (Albany NY) http://www.kidney.de/pget.php?&tw=1&pmid=33065551 #FOAvip The ongoing outbreak of COVID-19 has been announced by the World Health Organization as a worldwide public health emergency. The aim of this study was to distinguish between severe and non-severe patients in early diagnosis. The results showed that the mortality of COVID-19 patients increased accompanied by age. Host factors CRP, IL-1beta, hs-CRP, IL-8, and IL-6 levels in severe pneumonia patients were higher than in non-severe patients. CD3, CD8, and CD45 counts were decreased in COVID-19 patients. The results of this study suggest that the K-values of CD45 might be useful in distinguishing between severe and non-severe cases. The cut-off value for CD45 was -94.33. The K-values for CD45 in non-severe case were above the cut-off values, indicating a 100% prediction success rate for severe and non-severe cases following SARS-CoV-2 infection. The results confirmed that immune system dysfunction is a potential cause of mortality following COVID-19 infection, particularly for the elderly. CD45 deficiency dysfunction the naive and memory T lymphocytes which may affects the long-term effectiveness of COVID-19 vaccines. K-values of CD45 might be useful in distinguishing between severe and non-severe cases in the early infection. May be CD45 could increase the diagnostic sensitivity. Twit Text FOAVip CD45: a critical regulator in immune cells to predict severe and non-severe COVID-19 patients ????Aging (Albany NY) http://www.kidney.de/pget.php?&tw=1&pmid=33065551 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33065551 #FOAvip English Wikipedia <ref>{{Cite pmid|33065551}}</ref> CD45: a critical regulator in immune cells to predict severe and non-severe COVID-19 patients #MMPMID33065551 Jin M; Shi N; Wang M; Shi C; Lu S; Chang Q; Sha S; Lin Y; Chen Y; Zhou H; Liang K; Huang X; Shi Y; Huang G Aging (Albany NY) 2020[Oct]; 12 (20): 19867-19879 PMID33065551show ga The ongoing outbreak of COVID-19 has been announced by the World Health Organization as a worldwide public health emergency. The aim of this study was to distinguish between severe and non-severe patients in early diagnosis. The results showed that the mortality of COVID-19 patients increased accompanied by age. Host factors CRP, IL-1beta, hs-CRP, IL-8, and IL-6 levels in severe pneumonia patients were higher than in non-severe patients. CD3, CD8, and CD45 counts were decreased in COVID-19 patients. The results of this study suggest that the K-values of CD45 might be useful in distinguishing between severe and non-severe cases. The cut-off value for CD45 was -94.33. The K-values for CD45 in non-severe case were above the cut-off values, indicating a 100% prediction success rate for severe and non-severe cases following SARS-CoV-2 infection. The results confirmed that immune system dysfunction is a potential cause of mortality following COVID-19 infection, particularly for the elderly. CD45 deficiency dysfunction the naive and memory T lymphocytes which may affects the long-term effectiveness of COVID-19 vaccines. K-values of CD45 might be useful in distinguishing between severe and non-severe cases in the early infection. May be CD45 could increase the diagnostic sensitivity. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Betacoronavirus/*immunology[MESH] |CD3 Complex/*deficiency[MESH] |COVID-19[MESH] |Coronavirus Infections/blood/diagnosis/*immunology/virology[MESH] |Early Diagnosis[MESH] |Female[MESH] |Host-Pathogen Interactions/*immunology[MESH] |Humans[MESH] |Leukocyte Common Antigens/*deficiency[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/blood/diagnosis/*immunology/virology[MESH] |Retrospective Studies[MESH] |SARS-CoV-2[MESH]CD45: a critical regulator in immune cells to predict severe and non-s(epmc).pdf DeepDyve Pubget Overpricing