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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Lancet 2020 ; 396 (10262): 1595-1606 Nephropedia Template TP
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SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates #MMPMID33065034
Poland GA; Ovsyannikova IG; Kennedy RB
Lancet 2020[Nov]; 396 (10262): 1595-1606 PMID33065034show ga
Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such as hyperimmune globulin and convalescent human plasma, and to developing vaccines, antivirals, and monoclonal antibodies. A mere 11 months ago, the canvas we call COVID-19 was blank. Scientists around the world have worked collaboratively to fill in this blank canvas. In this Review, we discuss what is currently known about human humoral and cellular immune responses to severe acute respiratory syndrome coronavirus 2 and relate this knowledge to the COVID-19 vaccines currently in phase 3 clinical trials.