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10.1093/infdis/jiaa656

http://scihub22266oqcxt.onion/10.1093/infdis/jiaa656
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33064789!7665624!33064789
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suck abstract from ncbi


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pmid33064789      J+Infect+Dis 2021 ; 223 (5): 796-801
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  • Independent Side-by-Side Validation and Comparison of 4 Serological Platforms for SARS-CoV-2 Antibody Testing #MMPMID33064789
  • Jahrsdorfer B; Kroschel J; Ludwig C; Corman VM; Schwarz T; Korper S; Rojewski M; Lotfi R; Weinstock C; Drosten C; Seifried E; Stamminger T; Gross HJ; Schrezenmeier H
  • J Infect Dis 2021[Mar]; 223 (5): 796-801 PMID33064789show ga
  • Highly sensitive and specific platforms for the detection of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies are becoming increasingly important for evaluating potential SARS-CoV-2 convalescent plasma donors, studying the spread of SARS-CoV-2 infections, and identifying individuals with seroconversion. This study provides a comparative validation of 4 anti-SARS-CoV-2 platforms. A unique feature of the study is the use of a representative cohort of convalescent patients with coronavirus disease 2019 and a mild to moderate disease course. All platforms showed significant correlations with a SARS-CoV-2 plaque reduction neutralization test, with highest sensitivities for the Euroimmun and the Roche platforms, suggesting their preferential use for screening persons at increased risk of SARS-CoV-2 infections.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19 Serological Testing/methods/*standards[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |COVID-19/*therapy[MESH]
  • |Case-Control Studies[MESH]
  • |Cohort Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunization, Passive/standards[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neutralization Tests[MESH]
  • |Predictive Value of Tests[MESH]
  • |SARS-CoV-2/*immunology[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Tissue Donors[MESH]


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