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10.3343/alm.2021.41.2.129 http://scihub22266oqcxt.onion/10.3343/alm.2021.41.2.129 33063674!7591285!33063674     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ann+Lab+Med 2021 ; 41 (2): 129-138 Nephropedia Template TP {{tp|p=33063674|t=2021. Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19 |pdf=|usr=}}{{33063674}} gab.com Text Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19 JO: Ann Lab Med http://www.kidney.de/pget.php?&tw=1&pmid=33063674 #FOAvip Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly all countries worldwide. As the COVID-19 pandemic progresses, the need to identify genetic risk factors for susceptibility to this serious illness has emerged. Host genetic factors, along with other risk factors may help determine susceptibility to respiratory tract infections. It is hypothesized that the ACE2 gene, encoding angiotensin-converting enzyme 2 (ACE2), is a genetic risk factor for SARS-CoV-2 infection and is required by the virus to enter cells. Together with ACE2, transmembrane protease serine 2 (TMPRSS2) and dipeptidyl peptidase-4 (DPP4) also play an important role in disease severity. Evaluating the role of genetic variants in determining the direction of respiratory infections will help identify potential drug target candidates for further study in COVID-19 patients. We have summarized the latest reports demonstrating that ACE2 variants, their expression, and epigenetic factors may influence an individual's susceptibility to SARS-CoV-2 infection and disease outcome. Twit Text FOAVip Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19 ????Ann Lab Med http://www.kidney.de/pget.php?&tw=1&pmid=33063674 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33063674 #FOAvip English Wikipedia <ref>{{Cite pmid|33063674}}</ref> Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19 #MMPMID33063674 Choudhary S; Sreenivasulu K; Mitra P; Misra S; Sharma P Ann Lab Med 2021[Mar]; 41 (2): 129-138 PMID33063674show ga Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly all countries worldwide. As the COVID-19 pandemic progresses, the need to identify genetic risk factors for susceptibility to this serious illness has emerged. Host genetic factors, along with other risk factors may help determine susceptibility to respiratory tract infections. It is hypothesized that the ACE2 gene, encoding angiotensin-converting enzyme 2 (ACE2), is a genetic risk factor for SARS-CoV-2 infection and is required by the virus to enter cells. Together with ACE2, transmembrane protease serine 2 (TMPRSS2) and dipeptidyl peptidase-4 (DPP4) also play an important role in disease severity. Evaluating the role of genetic variants in determining the direction of respiratory infections will help identify potential drug target candidates for further study in COVID-19 patients. We have summarized the latest reports demonstrating that ACE2 variants, their expression, and epigenetic factors may influence an individual's susceptibility to SARS-CoV-2 infection and disease outcome. |*Genetic Variation[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Betacoronavirus/*genetics/isolation & purification[MESH] |COVID-19[MESH] |Coronavirus Infections/*pathology/virology[MESH] |Dipeptidyl Peptidase 4/genetics/metabolism[MESH] |Disease Susceptibility[MESH] |Gene Expression[MESH] |Humans[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/chemistry/genetics/metabolism[MESH] |Pneumonia, Viral/*pathology/virology[MESH] |SARS-CoV-2[MESH] |Serine Endopeptidases/genetics/metabolism[MESH]Role of Genetic Variants and Gene Expression in the Susceptibility and(epmc).pdf DeepDyve Pubget Overpricing