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Asymptomatic Subclinical Cases of Coronavirus Disease 2019 without Viral Transmission in Three Independent Families #MMPMID33061473
Zhang X; Chen L; Wei J; Zhou J; Cao Y; Wang G
Infect Drug Resist 2020[]; 13 (?): 3267-3271 PMID33061473show ga
PURPOSE: There is increasing evidence indicating that considerable fractions of cases of SARS-CoV-2 infection are asymptomatic. We traced three asymptomatic clusters to investigate the infectivity of subclinical cases of coronavirus disease 2019 (COVID-19). PATIENTS AND METHODS: Three medical staff who were asymptomatic were diagnosed with coronavirus disease 2019 by serological tests. Their close contacts were systematically evaluated based on COVID-19-related symptoms, nucleic acid tests, serological tests, and chest computed tomography (CT) as needed to determine if they were infected by SARS-CoV-2. RESULTS: None of the staff's close contacts, including 10 family members, were infected by the indexes, even though no protective measures were taken. CONCLUSION: The infectivity of asymptomatic subclinical infection patients of coronavirus disease 2019 seems to be low.