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10.2147/DDDT.S269407 http://scihub22266oqcxt.onion/10.2147/DDDT.S269407 33061304!7533900!33061304     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Drug+Des+Devel+Ther 2020 ; 14 (ä): 3995-4001 Nephropedia Template TP {{tp|p=33061304|t=2020. Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19 |pdf=|usr=}}{{33061304}} gab.com Text Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19 JO: Drug Des Devel Ther http://www.kidney.de/pget.php?&tw=1&pmid=33061304 #FOAvip The coronavirus disease 2019 (COVID-19) global pandemic continues and antiviral agents and vaccines are currently under investigation. Mesenchymal stem cell (MSC)-based therapy can be a suitable option for management of patients with COVID-19 at the urgent time of virus outbreak. Currently, MSCs are being explored against the novel infectious disease due to their therapeutic properties of anti-inflammation, immunomodulation and tissue repair and regeneration, albeit the precise mechanisms of MSC action toward COVID-19 remain unclear. To date, rigorous results from clinical trials using MSCs in human have been weakly positive. The pervasive uncertainty of using MSC therapeutic products as an effective combatant against COVID-19 requires rigorous resolution on several fronts, including MSC fate after infusion, safety issue, homing capability, and MSC resistance to the disease microenvironment. Focusing on these facets, a few important ones will be critically analyzed and addressed in this article for the development of safe and effective MSC-based therapies for COVID-19. Twit Text FOAVip Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19 ????Drug Des Devel Ther http://www.kidney.de/pget.php?&tw=1&pmid=33061304 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33061304 #FOAvip English Wikipedia <ref>{{Cite pmid|33061304}}</ref> Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19 #MMPMID33061304 Li C; Zhao H; Wang B Drug Des Devel Ther 2020[]; 14 (ä): 3995-4001 PMID33061304show ga The coronavirus disease 2019 (COVID-19) global pandemic continues and antiviral agents and vaccines are currently under investigation. Mesenchymal stem cell (MSC)-based therapy can be a suitable option for management of patients with COVID-19 at the urgent time of virus outbreak. Currently, MSCs are being explored against the novel infectious disease due to their therapeutic properties of anti-inflammation, immunomodulation and tissue repair and regeneration, albeit the precise mechanisms of MSC action toward COVID-19 remain unclear. To date, rigorous results from clinical trials using MSCs in human have been weakly positive. The pervasive uncertainty of using MSC therapeutic products as an effective combatant against COVID-19 requires rigorous resolution on several fronts, including MSC fate after infusion, safety issue, homing capability, and MSC resistance to the disease microenvironment. Focusing on these facets, a few important ones will be critically analyzed and addressed in this article for the development of safe and effective MSC-based therapies for COVID-19. |*Mesenchymal Stem Cell Transplantation/adverse effects[MESH] |Animals[MESH] |Betacoronavirus/immunology/*pathogenicity[MESH] |COVID-19[MESH] |Coronavirus Infections/diagnosis/immunology/*surgery/virology[MESH] |Host-Pathogen Interactions[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/diagnosis/immunology/*surgery/virology[MESH] |SARS-CoV-2[MESH]Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19 (epmc).pdf DeepDyve Pubget Overpricing