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10.1038/s41598-020-74284-6

http://scihub22266oqcxt.onion/10.1038/s41598-020-74284-6
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33060676!7562721!33060676
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suck abstract from ncbi


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pmid33060676      Sci+Rep 2020 ; 10 (1): 17365
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  • Clinical characteristics of "re-positive" discharged COVID-19 pneumonia patients in Wuhan, China #MMPMID33060676
  • He S; Zhou K; Hu M; Liu C; Xie L; Sun S; Sun W; Chen L
  • Sci Rep 2020[Oct]; 10 (1): 17365 PMID33060676show ga
  • To analyze the clinical characteristics of re-positive discharged COVID-19 patients and find distinguishing markers. The demographic features, clinical symptoms, laboratory results, comorbidities, co-infections, treatments, illness severities and chest CT scan results of 267 patients were collected from 1st January to 15th February 2020. COVID-19 was diagnosed by RT-PCR. Clinical symptoms and nucleic acid test results were collected during the 14 days post-hospitalization quarantine. 30 out of 267 COVID-19 patients were detected re-positive during the post-hospitalization quarantine. Re-positive patients could not be distinguished by demographic features, clinical symptoms, laboratory results, comorbidities, co-infections, treatments, chest CT scan results or subsequent clinical symptoms. However, re-positive rate was found to be correlated to illness severity, according the Acute Physiology and Chronic Health Evaluation II (APACHE II) severity-of-disease classification system, and the confusion, urea, respiratory rate and blood pressure (CURB-65) score. Common clinical characteristics were not able to distinguish re-positive patients. However, severe and critical cases classified high according APACHE II and CURB-65 scores, were more likely to become re-positive after discharge.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Betacoronavirus/*genetics/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |China[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*pathology/virology[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Logistic Models[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Patient Discharge[MESH]
  • |Pneumonia, Viral/*pathology/virology[MESH]
  • |Quarantine[MESH]
  • |RNA, Viral/metabolism[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Thorax/diagnostic imaging[MESH]


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