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10.1016/j.jmii.2020.09.002

http://scihub22266oqcxt.onion/10.1016/j.jmii.2020.09.002
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33060041!7534785!33060041
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suck abstract from ncbi


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pmid33060041      J+Microbiol+Immunol+Infect 2021 ; 54 (1): 27-36
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  • Remdesivir use in the coronavirus disease 2019 pandemic: A mini-review #MMPMID33060041
  • Yang CJ; Wei YJ; Chang HL; Chang PY; Tsai CC; Chen YH; Hsueh PR
  • J Microbiol Immunol Infect 2021[Feb]; 54 (1): 27-36 PMID33060041show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative viral pathogen of coronavirus disease 2019 (COVID-19), appears to have various clinical presentations and may result in severe respiratory failure. The global SARS-CoV-2-associated viral pneumonia pandemic was first reported in December 2019 in China. Based on known pharmacological mechanisms, many therapeutic drugs have been repurposed to target SARS-CoV-2. Among these drugs, remdesivir appears to be the currently most promising according to several clinical trials and reports of compassionate use. In this mini-review, we summarize the current evidence on the efficacy and challenges of remdesivir for the treatment of coronavirus disease 2019 (COVID-19).
  • |*COVID-19 Drug Treatment[MESH]
  • |Adenosine Monophosphate/administration & dosage/*analogs & derivatives[MESH]
  • |Alanine/administration & dosage/*analogs & derivatives[MESH]
  • |Antiviral Agents/*administration & dosage[MESH]
  • |COVID-19/epidemiology[MESH]
  • |China/epidemiology[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Randomized Controlled Trials as Topic[MESH]


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