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10.1016/j.virol.2020.08.018 http://scihub22266oqcxt.onion/10.1016/j.virol.2020.08.018 33059319!7548064!33059319     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33059319&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Virology 2021 ; 552 (ä): 43-51 Nephropedia Template TP {{tp|p=33059319|t=2021. Epithelial-mesenchymal transition of absorptive enterocytes and depletion of Peyer s patch M cells after PEDV infection |pdf=|usr=}}{{33059319}} gab.com Text Epithelial-mesenchymal transition of absorptive enterocytes and depletion of Peyer s patch M cells after PEDV infection JO: Virology http://www.kidney.de/pget.php?&tw=1&pmid=33059319 #FOAvip This study focused on intestinal restitution including phenotype switching of absorptive enterocytes and the abundance of different enterocyte subtypes in weaned pigs after porcine epidemic diarrhea virus (PEDV) infection. At 10 days post-PEDV-inoculation, the ratio of villus height to crypt depth in both jejunum and ileum had restored, and the PEDV antigen was not detectable. However, enterocytes at the villus tips revealed epithelial-mesenchymal transition (EMT) in the jejunum in which E-cadherin expression decreased while expression of N-cadherin, vimentin, and Snail increased. Additionally, there was reduced expression of actin in microvilli and Zonula occludens-1 (ZO-1) in tight junctions. Moreover, the protein concentration of transforming growth factor beta1 (TGFbeta1), which mediates EMT and cytoskeleton alteration, was increased. We also found a decreased number of Peyer's patch M cells in the ileum. These results reveal incomplete restitution of enterocytes in the jejunum and potentially impaired immune surveillance in the ileum after PEDV infection. Twit Text FOAVip Epithelial-mesenchymal transition of absorptive enterocytes and depletion of Peyer s patch M cells after PEDV infection ????Virology http://www.kidney.de/pget.php?&tw=1&pmid=33059319 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33059319 #FOAvip English Wikipedia <ref>{{Cite pmid|33059319}}</ref> Epithelial-mesenchymal transition of absorptive enterocytes and depletion of Peyer s patch M cells after PEDV infection #MMPMID33059319 Chen YM; Helm ET; Groeltz-Thrush JM; Gabler NK; Burrough ER Virology 2021[Jan]; 552 (ä): 43-51 PMID33059319show ga This study focused on intestinal restitution including phenotype switching of absorptive enterocytes and the abundance of different enterocyte subtypes in weaned pigs after porcine epidemic diarrhea virus (PEDV) infection. At 10 days post-PEDV-inoculation, the ratio of villus height to crypt depth in both jejunum and ileum had restored, and the PEDV antigen was not detectable. However, enterocytes at the villus tips revealed epithelial-mesenchymal transition (EMT) in the jejunum in which E-cadherin expression decreased while expression of N-cadherin, vimentin, and Snail increased. Additionally, there was reduced expression of actin in microvilli and Zonula occludens-1 (ZO-1) in tight junctions. Moreover, the protein concentration of transforming growth factor beta1 (TGFbeta1), which mediates EMT and cytoskeleton alteration, was increased. We also found a decreased number of Peyer's patch M cells in the ileum. These results reveal incomplete restitution of enterocytes in the jejunum and potentially impaired immune surveillance in the ileum after PEDV infection. |*Epithelial-Mesenchymal Transition[MESH] |Animals[MESH] |Cadherins/metabolism[MESH] |Coronavirus Infections/immunology/pathology/*veterinary/virology[MESH] |Enterocytes/*pathology[MESH] |Gastroenteritis, Transmissible, of Swine/immunology/*pathology/virology[MESH] |Ileum/immunology/pathology[MESH] |Intestinal Mucosa/pathology[MESH] |Jejunum/immunology/pathology[MESH] |Microvilli/pathology[MESH] |Peyer's Patches/*pathology[MESH] |Porcine epidemic diarrhea virus/*pathogenicity[MESH] |Swine[MESH] |Tight Junctions/pathology[MESH] |Transforming Growth Factor beta1/metabolism[MESH]Epithelial-mesenchymal transition of absorptive enterocytes and deplet(epmc).pdf DeepDyve Pubget Overpricing