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10.1038/s41597-020-00668-y http://scihub22266oqcxt.onion/10.1038/s41597-020-00668-y 33057040!7566589!33057040     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Data 2020 ; 7 (1): 329 Nephropedia Template TP {{tp|p=33057040|t=2020. Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age children |pdf=|usr=}}{{33057040}} gab.com Text Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age children JO: Sci Data http://www.kidney.de/pget.php?&tw=1&pmid=33057040 #FOAvip The COVID-19 pandemic has ignited interest in age-specific manifestations of infection but surprisingly little is known about relative severity of infectious disease between the extremes of age. In a systematic analysis we identified 142 datasets with information on severity of disease by age for 32 different infectious diseases, 19 viral and 13 bacterial. For almost all infections, school-age children have the least severe disease, and severity starts to rise long before old age. Indeed, for many infections even young adults have more severe disease than children, and dengue was the only infection that was most severe in school-age children. Together with data on vaccine response in children and young adults, the findings suggest peak immune function is reached around 5-14 years of age. Relative immune senescence may begin much earlier than assumed, before accelerating in older age groups. This has major implications for understanding resilience to infection, optimal vaccine scheduling, and appropriate health protection policies across the life course. Twit Text FOAVip Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age children ????Sci Data http://www.kidney.de/pget.php?&tw=1&pmid=33057040 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33057040 #FOAvip English Wikipedia <ref>{{Cite pmid|33057040}}</ref> Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age children #MMPMID33057040 Glynn JR; Moss PAH Sci Data 2020[Oct]; 7 (1): 329 PMID33057040show ga The COVID-19 pandemic has ignited interest in age-specific manifestations of infection but surprisingly little is known about relative severity of infectious disease between the extremes of age. In a systematic analysis we identified 142 datasets with information on severity of disease by age for 32 different infectious diseases, 19 viral and 13 bacterial. For almost all infections, school-age children have the least severe disease, and severity starts to rise long before old age. Indeed, for many infections even young adults have more severe disease than children, and dengue was the only infection that was most severe in school-age children. Together with data on vaccine response in children and young adults, the findings suggest peak immune function is reached around 5-14 years of age. Relative immune senescence may begin much earlier than assumed, before accelerating in older age groups. This has major implications for understanding resilience to infection, optimal vaccine scheduling, and appropriate health protection policies across the life course. |*Age Factors[MESH] |Adolescent[MESH] |Adult[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |Child[MESH] |Child, Preschool[MESH] |Communicable Diseases/*immunology/mortality[MESH] |Coronavirus Infections[MESH] |Datasets as Topic[MESH] |Humans[MESH] |Immunosenescence[MESH] |Pandemics[MESH] |Pneumonia, Viral[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]Systematic analysis of infectious disease outcomes by age shows lowest(epmc).pdf DeepDyve Pubget Overpricing