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10.1038/s41598-020-73788-5

http://scihub22266oqcxt.onion/10.1038/s41598-020-73788-5
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suck abstract from ncbi


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pmid33057039      Sci+Rep 2020 ; 10 (1): 17236
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  • Coronavirus disease 2019 (COVID-19) in Italy: features on chest computed tomography using a structured report system #MMPMID33057039
  • Grassi R; Fusco R; Belfiore MP; Montanelli A; Patelli G; Urraro F; Petrillo A; Granata V; Sacco P; Mazzei MA; Feragalli B; Reginelli A; Cappabianca S
  • Sci Rep 2020[Oct]; 10 (1): 17236 PMID33057039show ga
  • To assess the use of a structured report in the Chest Computed Tomography (CT) reporting of patients with suspicious viral pneumonia by COVID-19 and the evaluation of the main CT patterns. This study included 134 patients (43 women and 91 men; 68.8 years of mean age, range 29-93 years) with suspicious COVID-19 viral infection evaluated by reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test. All patients underwent CT examinations at the time of admission. CT images were reviewed by two radiologists who identified COVID-19 CT patterns using a structured reports. Temporal difference mean value between RT-PCRs and CT scan was 0.18 days +/- 2.0 days. CT findings were positive for viral pneumonia in 94.0% patients while COVID-19 was diagnosed at RT-PCR in 77.6% patients. Time mean value to complete the structured report by radiologist was 8.5 min +/- 2.4 min. The disease on chest CT predominantly affected multiple lobes and the main CT feature was ground glass opacity (GGO) with or without consolidation (96.8%). GGO was predominantly bilateral (89.3%), peripheral (80.3%), multifocal/patching (70.5%). Consolidation disease was predominantly bilateral (83.9%) with prevalent peripheral (87.1%) and segmental (47.3%) distribution. Additional CT signs were the crazy-paving pattern in 75.4% of patients, the septal thickening in 37.3% of patients, the air bronchogram sign in 39.7% and the "reversed halo" sign in 23.8%. Less frequent characteristics at CT regard discrete pulmonary nodules, increased trunk diameter of the pulmonary artery, pleural effusion and pericardium effusion (7.9%, 6.3%, 14.3% and 16.7%, respectively). Barotrauma sign was absent in all the patients. High percentage (54.8%) of the patients had mediastinal lymphadenopathy. Using a Chest CT structured report, with a standardized language, we identified that the cardinal hallmarks of COVID-19 infection were bilateral, peripheral and multifocal/patching GGO and bilateral consolidation with peripheral and segmental distribution.
  • |*Electronic Health Records[MESH]
  • |*Tomography, X-Ray Computed[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus/genetics/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*diagnosis/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Italy[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/virology[MESH]
  • |RNA, Viral/metabolism[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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