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10.1038/s41467-020-18880-0 http://scihub22266oqcxt.onion/10.1038/s41467-020-18880-0 33057007!7560817!33057007     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2020 ; 11 (1): 5165 Nephropedia Template TP {{tp|p=33057007|t=2020. ACE2 mouse models: a toolbox for cardiovascular and pulmonary research |pdf=|usr=}}{{33057007}} gab.com Text ACE2 mouse models: a toolbox for cardiovascular and pulmonary research JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33057007 #FOAvip Angiotensin-converting enzyme 2 (ACE2) has been identified as the host entry receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 pandemic. ACE2 is a regulatory enzyme of the renin-angiotensin system and has protective functions in many cardiovascular, pulmonary and metabolic diseases. This review summarizes available murine models with systemic or organ-specific deletion of ACE2, or with overexpression of murine or human ACE2. The purpose of this review is to provide researchers with the genetic tools available for further understanding of ACE2 biology and for the investigation of ACE2 in the pathogenesis and treatment of COVID-19. Twit Text FOAVip ACE2 mouse models: a toolbox for cardiovascular and pulmonary research ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33057007 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33057007 #FOAvip English Wikipedia <ref>{{Cite pmid|33057007}}</ref> ACE2 mouse models: a toolbox for cardiovascular and pulmonary research #MMPMID33057007 Jia H; Yue X; Lazartigues E Nat Commun 2020[Oct]; 11 (1): 5165 PMID33057007show ga Angiotensin-converting enzyme 2 (ACE2) has been identified as the host entry receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 pandemic. ACE2 is a regulatory enzyme of the renin-angiotensin system and has protective functions in many cardiovascular, pulmonary and metabolic diseases. This review summarizes available murine models with systemic or organ-specific deletion of ACE2, or with overexpression of murine or human ACE2. The purpose of this review is to provide researchers with the genetic tools available for further understanding of ACE2 biology and for the investigation of ACE2 in the pathogenesis and treatment of COVID-19. |*Disease Models, Animal[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Animals[MESH] |Betacoronavirus/physiology[MESH] |COVID-19[MESH] |Cardiovascular Diseases/metabolism/*pathology[MESH] |Coronavirus Infections/metabolism/pathology/virology[MESH] |Humans[MESH] |Lung Diseases/metabolism/*pathology[MESH] |Metabolic Diseases/metabolism/pathology[MESH] |Mice[MESH] |Mice, Mutant Strains[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/genetics/*metabolism[MESH] |Pneumonia, Viral/metabolism/pathology/virology[MESH]ACE2 mouse models: a toolbox for cardiovascular and pulmonary research(epmc).pdf DeepDyve Pubget Overpricing