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10.1097/INF.0000000000002949 http://scihub22266oqcxt.onion/10.1097/INF.0000000000002949 33055501!ä!33055501 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Infect+Dis+J 2021 ; 40 (1): e1-e6 Nephropedia Template TP {{tp|p=33055501|t=2021. COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children: A Multinational Study |pdf=|usr=}}{{33055501}} gab.com Text COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children: A Multinational Study JO: Pediatr Infect Dis J http://www.kidney.de/pget.php?&tw=1&pmid=33055501 #FOAvip BACKGROUND: To date, there are no comprehensive data on pediatric COVID-19 from Latin America. This study aims to assess COVID-19 and Multisystem Inflammatory Syndrome (MIS-C) in Latin American children, to appropriately plan and allocate resources to face the pandemic on a local and international level. METHODS: Ambispective multicenter cohort study from 5 Latin American countries. Children 18 years of age or younger with microbiologically confirmed SARS-CoV-2 infection or fulfilling MIS-C definition were included. FINDINGS: Four hundred nine children were included, with a median age of 3.0 years (interquartile range 0.6-9.0). Of these, 95 (23.2%) were diagnosed with MIS-C. One hundred ninety-one (46.7%) children were admitted to hospital and 52 (12.7%) required admission to a pediatric intensive care unit. Ninety-two (22.5%) patients required oxygen support: 8 (2%) were started on continuous positive airway pressure and 29 (7%) on mechanical ventilation. Thirty-five (8.5%) patients required inotropic support. The following factors were associated with pediatric intensive care unit admission: preexisting medical condition (P < 0.0001), immunodeficiency (P = 0.01), lower respiratory tract infection (P < 0.0001), gastrointestinal symptoms (P = 0.006), radiologic changes suggestive of pneumonia and acute respiratory distress syndrome (P < 0.0001) and low socioeconomic conditions (P = 0.009). CONCLUSIONS: This study shows a generally more severe form of COVID-19 and a high number of MIS-C in Latin American children, compared with studies from China, Europe and North America, and support current evidence of a more severe disease in Latin/Hispanic children or in people of lower socioeconomic level. The findings highlight an urgent need for more data on COVID-19 in Latin America. Twit Text FOAVip COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children: A Multinational Study ????Pediatr Infect Dis J http://www.kidney.de/pget.php?&tw=1&pmid=33055501 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33055501 #FOAvip English Wikipedia <ref>{{Cite pmid|33055501}}</ref> COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children: A Multinational Study #MMPMID33055501 Antunez-Montes OY; Escamilla MI; Figueroa-Uribe AF; Arteaga-Menchaca E; Lavariega-Sarachaga M; Salcedo-Lozada P; Melchior P; de Oliveira RB; Tirado Caballero JC; Redondo HP; Montes Fontalvo LV; Hernandez R; Chavez C; Campos F; Uribe F; Del Aguila O; Rios Aida JA; Buitrago AP; Betancur Londono LM; Mendoza Vega LF; Hernandez CA; Sali M; Higuita Palacio JE; Gomez-Vargas J; Yock-Corrales A; Buonsenso D Pediatr Infect Dis J 2021[Jan]; 40 (1): e1-e6 PMID33055501show ga BACKGROUND: To date, there are no comprehensive data on pediatric COVID-19 from Latin America. This study aims to assess COVID-19 and Multisystem Inflammatory Syndrome (MIS-C) in Latin American children, to appropriately plan and allocate resources to face the pandemic on a local and international level. METHODS: Ambispective multicenter cohort study from 5 Latin American countries. Children 18 years of age or younger with microbiologically confirmed SARS-CoV-2 infection or fulfilling MIS-C definition were included. FINDINGS: Four hundred nine children were included, with a median age of 3.0 years (interquartile range 0.6-9.0). Of these, 95 (23.2%) were diagnosed with MIS-C. One hundred ninety-one (46.7%) children were admitted to hospital and 52 (12.7%) required admission to a pediatric intensive care unit. Ninety-two (22.5%) patients required oxygen support: 8 (2%) were started on continuous positive airway pressure and 29 (7%) on mechanical ventilation. Thirty-five (8.5%) patients required inotropic support. The following factors were associated with pediatric intensive care unit admission: preexisting medical condition (P < 0.0001), immunodeficiency (P = 0.01), lower respiratory tract infection (P < 0.0001), gastrointestinal symptoms (P = 0.006), radiologic changes suggestive of pneumonia and acute respiratory distress syndrome (P < 0.0001) and low socioeconomic conditions (P = 0.009). CONCLUSIONS: This study shows a generally more severe form of COVID-19 and a high number of MIS-C in Latin American children, compared with studies from China, Europe and North America, and support current evidence of a more severe disease in Latin/Hispanic children or in people of lower socioeconomic level. The findings highlight an urgent need for more data on COVID-19 in Latin America. |Adolescent[MESH] |COVID-19/diagnosis/*epidemiology/*pathology/therapy[MESH] |Child[MESH] |Child, Preschool[MESH] |Cohort Studies[MESH] |Critical Care[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Latin America/epidemiology[MESH] |Male[MESH] |Risk Factors[MESH] |SARS-CoV-2/isolation & purification[MESH]COVID-19 and Multisystem Inflammatory Syndrome in Latin American Child(epmc).pdf DeepDyve Pubget Overpricing