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10.3324/haematol.2020.264267 http://scihub22266oqcxt.onion/10.3324/haematol.2020.264267 33054129!7716349!33054129     free     free     free       Haematologica 2020 ; 105 (12): 2769-2773 Nephropedia Template TP {{tp|p=33054129|t=2020. No evidence of hemoglobin damage by SARS-CoV-2 infection |pdf=|usr=}}{{33054129}} gab.com Text No evidence of hemoglobin damage by SARS-CoV-2 infection JO: Haematologica http://www.kidney.de/pget.php?&tw=1&pmid=33054129 #FOAvip SARS-CoV-2 disease (COVID-19) has affected over 22 million patients worldwide as of August 2020. As the medical community seeks better understanding of the underlying pathophysiology of COVID-19, several theories have been proposed. One widely shared theory suggests that SARS-CoV-2 proteins directly interact with human hemoglobin (Hb) and facilitate removal of iron from the heme prosthetic group, leading to the loss of functional hemoglobin and accumulation of iron. Herein, we refute this theory. We compared clinical data from 21 critically ill COVID-19 patients to 21 non-COVID-19 ARDS patient controls, generating hemoglobin-oxygen dissociation curves from venous blood gases. This curve generated from the COVID-19 cohort matched the idealized oxygen-hemoglobin dissociation curve well (Pearson correlation, R2 = 0.97, P. Twit Text FOAVip No evidence of hemoglobin damage by SARS-CoV-2 infection ????Haematologica http://www.kidney.de/pget.php?&tw=1&pmid=33054129 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33054129 #FOAvip English Wikipedia <ref>{{Cite pmid|33054129}}</ref> No evidence of hemoglobin damage by SARS-CoV-2 infection #MMPMID33054129 DeMartino AW; Rose JJ; Amdahl MB; Dent MR; Shah FA; Bain W; McVerry BJ; Kitsios GD; Tejero J; Gladwin MT Haematologica 2020[Dec]; 105 (12): 2769-2773 PMID33054129show ga SARS-CoV-2 disease (COVID-19) has affected over 22 million patients worldwide as of August 2020. As the medical community seeks better understanding of the underlying pathophysiology of COVID-19, several theories have been proposed. One widely shared theory suggests that SARS-CoV-2 proteins directly interact with human hemoglobin (Hb) and facilitate removal of iron from the heme prosthetic group, leading to the loss of functional hemoglobin and accumulation of iron. Herein, we refute this theory. We compared clinical data from 21 critically ill COVID-19 patients to 21 non-COVID-19 ARDS patient controls, generating hemoglobin-oxygen dissociation curves from venous blood gases. This curve generated from the COVID-19 cohort matched the idealized oxygen-hemoglobin dissociation curve well (Pearson correlation, R2 = 0.97, P. |*Betacoronavirus[MESH] |Adult[MESH] |Aged[MESH] |COVID-19[MESH] |Cohort Studies[MESH] |Coronavirus Infections/*blood/*diagnosis[MESH] |Female[MESH] |Hemoglobins/*metabolism[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/*blood/*diagnosis[MESH] |Protein Binding/physiology[MESH]No evidence of hemoglobin damage by SARS-CoV-2 infection (epmc).pdf DeepDyve Pubget Overpricing