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10.1159/000511436

http://scihub22266oqcxt.onion/10.1159/000511436
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33049753!7649691!33049753
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suck abstract from ncbi


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pmid33049753      ORL+J+Otorhinolaryngol+Relat+Spec 2020 ; 82 (6): 295-303
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  • Short-Term Follow-Up of Self-Isolated COVID-19 Patients with Smell and Taste Dysfunction in Greece: Two Phenotypes of Recovery #MMPMID33049753
  • Konstantinidis I; Delides A; Tsakiropoulou E; Maragoudakis P; Sapounas S; Tsiodras S
  • ORL J Otorhinolaryngol Relat Spec 2020[]; 82 (6): 295-303 PMID33049753show ga
  • INTRODUCTION: The course of anosmia and ageusia in COVID-19 patients is not yet clearly known. We present short-term follow-up data concerning mild to moderate disease in home-quarantined COVID-19 patients in Greece. METHODS: We provided a symptom questionnaire and instructions for a self-administered home smell-and-taste test to 79 positive COVID-19 patients from 2 tertiary hospitals in Greece. The patients recorded their subjective symptoms before and during infection as well as 4 weeks after the diagnosis. The patients also underwent the home test during infection and 4 weeks later. RESULTS: Twenty-nine patients (36.7%) reported a loss of smell, and 21 (27.8%) reported a loss of taste, with equal prevalences between genders. We observed 2 types of recovery, i.e., a rapid, almost complete recovery, and a second slower and partial recovery. The type of recovery was not age related. A rapid recovery was observed in two thirds of the patients, with their olfactory ratings presenting a trend towards significance in correlation with nasal obstruction. A slow recovery in olfaction was correlated with low intensity ratings in odors with a trigeminal compound. The loss of taste was more pronounced in sweet and salty intensity ratings. CONCLUSION: Chemosensory deficits associated with COVID-19 infection were quite frequent among the Greek patients with mild or moderate disease who, in most cases, returned to normal within 4 weeks. However, 1 in 3 patients presented with persistent olfactory and gustatory dysfunction in the short term.
  • |*Recovery of Function[MESH]
  • |Adult[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Greece/epidemiology[MESH]
  • |Home Care Services[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Olfaction Disorders/*virology[MESH]
  • |Phenotype[MESH]
  • |Quarantine[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Surveys and Questionnaires[MESH]


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