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Using the common cold virus as a naturally occurring vaccine to prevent COVID-19: Lessons from Edward Jenner #MMPMID33049711
Sotgia F; Lisanti MP
Aging (Albany NY) 2020[Oct]; 12 (19): 18797-18803 PMID33049711show ga
Three recent papers published in Nature, Science and Cell, all present clear evidence that there is cross-reactive T-cell immunity between human coronaviruses (229E, NL63, OC43, and HKU1), linked with the common cold, and SARS-CoV-2, the causative agent of COVID-19. Can we use this information to design and build a new vaccine based on the less pathogenic, common cold coronaviruses, for the prevention of COVID-19? If we look at the history of medicine and vaccine development, from the point of view of Edward Jenner, the answer just might be yes.