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10.2741/874 http://scihub22266oqcxt.onion/10.2741/874 33048778!ä!33048778 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33048778&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Biosci+(Elite+Ed) 2021 ; 13 (1): 117-139 Nephropedia Template TP {{tp|p=33048778|t=2021. Insights into the COVID-19 pandemic: Origin, pathogenesis, diagnosis, and therapeutic interventions |pdf=|usr=}}{{33048778}} gab.com Text Insights into the COVID-19 pandemic: Origin, pathogenesis, diagnosis, and therapeutic interventions JO: Front Biosci (Elite Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33048778 #FOAvip Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the human coronavirus (HCoV) family that targets the lower part of the respiratory tract and causes severe acute respiratory syndrome (SARS). In a short span of time, this infection has led to a global pandemic and has become a significant threat to the existence of present human society. Currently, there are no treatments for this infection and the measures established across various countries such as social distancing, usage of mask to prevent entry of the virus into the respiratory tract, quarantine, and containment together have reduced the prevalence of this disease and mortality in highly susceptible individuals. Here, we examine the structure, replication cycle, phylogeny and genomic organization of this virus and discuss the role of spike (S) protein of the virus, an important structure that interacts with the host ACE2 receptor facilitating viral entry. Further, we explore the epidemiology, symptoms of the disease, describe the reverse transcriptase-polymerase chain reaction (RT-PCR) that establishes the diagnosis of the disease and also review its unique diagnostic features in the chest CT-Scan. Finally, we review the current approaches to develop therapies and vaccines as a measure for disease prevention and control. Twit Text FOAVip Insights into the COVID-19 pandemic: Origin, pathogenesis, diagnosis, and therapeutic interventions ????Front Biosci (Elite Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33048778 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33048778 #FOAvip English Wikipedia <ref>{{Cite pmid|33048778}}</ref> Insights into the COVID-19 pandemic: Origin, pathogenesis, diagnosis, and therapeutic interventions #MMPMID33048778 Berekaa MM Front Biosci (Elite Ed) 2021[Jan]; 13 (1): 117-139 PMID33048778show ga Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the human coronavirus (HCoV) family that targets the lower part of the respiratory tract and causes severe acute respiratory syndrome (SARS). In a short span of time, this infection has led to a global pandemic and has become a significant threat to the existence of present human society. Currently, there are no treatments for this infection and the measures established across various countries such as social distancing, usage of mask to prevent entry of the virus into the respiratory tract, quarantine, and containment together have reduced the prevalence of this disease and mortality in highly susceptible individuals. Here, we examine the structure, replication cycle, phylogeny and genomic organization of this virus and discuss the role of spike (S) protein of the virus, an important structure that interacts with the host ACE2 receptor facilitating viral entry. Further, we explore the epidemiology, symptoms of the disease, describe the reverse transcriptase-polymerase chain reaction (RT-PCR) that establishes the diagnosis of the disease and also review its unique diagnostic features in the chest CT-Scan. Finally, we review the current approaches to develop therapies and vaccines as a measure for disease prevention and control. |*Pandemics[MESH] |Betacoronavirus/*isolation & purification[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Clinical Laboratory Techniques/methods[MESH] |Coronavirus Infections/diagnosis/*epidemiology/therapy/virology[MESH] |Humans[MESH] |Pneumonia, Viral/diagnosis/*epidemiology/therapy/virology[MESH]Insights into the COVID-19 pandemic: Origin, pathogenesis, diagnosis, (epmc).pdf DeepDyve Pubget Overpricing