Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1007/s40292-020-00414-w http://scihub22266oqcxt.onion/10.1007/s40292-020-00414-w 33047250!7661400!33047250     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       High+Blood+Press+Cardiovasc+Prev 2020 ; 27 (6): 539-546 Nephropedia Template TP {{tp|p=33047250|t=2020. The role of Immunity in Fabry Disease and Hypertension: A Review of a Novel Common Pathway |pdf=|usr=}}{{33047250}} gab.com Text The role of Immunity in Fabry Disease and Hypertension: A Review of a Novel Common Pathway JO: High Blood Press Cardiovasc Prev http://www.kidney.de/pget.php?&tw=1&pmid=33047250 #FOAvip Fabry disease is a progressive, X-linked inherited lysosomal storage disorder where accumulation of glycosphingolipids increases the risk for early cardiovascular complications, including heart failure, stroke, and end stage renal disease. Besides disease-specific therapy, blood pressure (BP) control is of central importance in Fabry disease to reduce disease progression and improve prognosis. Both Fabry disease and hypertension are characterized by the activation of the innate component of the immune system, with Toll-like receptor 4 (TLR4) as a common trigger to the inflammatory cascade. The renin-angiotensin system (RAS) participates in the establishment of low-grade chronic inflammation and redox unbalance that contribute to organ damage in the long term. Besides exploiting the anti-inflammatory effects of RAS blockade and enzyme replacement therapy, targeted therapies acting on the immune system represent an appealing field of research in these conditions. The aim of this narrative review is to examine the issue of hypertension in the setting of Fabry disease, focusing on the possible determinants of their reciprocal relationship, as well as on the related clinical and therapeutic implications. Twit Text FOAVip The role of Immunity in Fabry Disease and Hypertension: A Review of a Novel Common Pathway ????High Blood Press Cardiovasc Prev http://www.kidney.de/pget.php?&tw=1&pmid=33047250 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33047250 #FOAvip English Wikipedia <ref>{{Cite pmid|33047250}}</ref> The role of Immunity in Fabry Disease and Hypertension: A Review of a Novel Common Pathway #MMPMID33047250 Del Pinto R; Ferri C High Blood Press Cardiovasc Prev 2020[Dec]; 27 (6): 539-546 PMID33047250show ga Fabry disease is a progressive, X-linked inherited lysosomal storage disorder where accumulation of glycosphingolipids increases the risk for early cardiovascular complications, including heart failure, stroke, and end stage renal disease. Besides disease-specific therapy, blood pressure (BP) control is of central importance in Fabry disease to reduce disease progression and improve prognosis. Both Fabry disease and hypertension are characterized by the activation of the innate component of the immune system, with Toll-like receptor 4 (TLR4) as a common trigger to the inflammatory cascade. The renin-angiotensin system (RAS) participates in the establishment of low-grade chronic inflammation and redox unbalance that contribute to organ damage in the long term. Besides exploiting the anti-inflammatory effects of RAS blockade and enzyme replacement therapy, targeted therapies acting on the immune system represent an appealing field of research in these conditions. The aim of this narrative review is to examine the issue of hypertension in the setting of Fabry disease, focusing on the possible determinants of their reciprocal relationship, as well as on the related clinical and therapeutic implications. |*Blood Pressure[MESH] |*Immunity, Innate/drug effects[MESH] |Animals[MESH] |Anti-Inflammatory Agents/therapeutic use[MESH] |Antihypertensive Agents/therapeutic use[MESH] |Antioxidants/therapeutic use[MESH] |Fabry Disease/drug therapy/*immunology/metabolism/physiopathology[MESH] |Humans[MESH] |Hypertension/drug therapy/*immunology/metabolism/physiopathology[MESH] |Inflammation Mediators/metabolism[MESH] |Inflammation/drug therapy/*immunology/metabolism/physiopathology[MESH] |Oxidative Stress[MESH] |Renin-Angiotensin System[MESH] |Signal Transduction[MESH]The role of Immunity in Fabry Disease and Hypertension: A Review of a (epmc).pdf DeepDyve Pubget Overpricing