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suck abstract from ncbi


10.1016/j.biologicals.2020.07.010

http://scihub22266oqcxt.onion/10.1016/j.biologicals.2020.07.010
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33041187!7543787!33041187
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suck abstract from ncbi


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pmid33041187      Biologicals 2020 ; 68 (ä): 92-107
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  • Animal testing for vaccines Implementing replacement, reduction and refinement: challenges and priorities #MMPMID33041187
  • Akkermans A; Chapsal JM; Coccia EM; Depraetere H; Dierick JF; Duangkhae P; Goel S; Halder M; Hendriksen C; Levis R; Pinyosukhee K; Pullirsch D; Sanyal G; Shi L; Sitrin R; Smith D; Stickings P; Terao E; Uhlrich S; Viviani L; Webster J
  • Biologicals 2020[Nov]; 68 (ä): 92-107 PMID33041187show ga
  • Transition to in vitro alternative methods from in vivo in vaccine release testing and characterization, the implementation of the consistency approach, and a drive towards international harmonization of regulatory requirements are most pressing needs in the field of vaccines. It is critical for global vaccine community to work together to secure effective progress towards animal welfare and to ensure that vaccines of ever higher quality can reach the populations in need in the shortest possible timeframe. Advancements in the field, case studies, and experiences from Low and Middle Income Countries (LMIC) were the topics discussed by an international gathering of experts during a recent conference titled "Animal Testing for Vaccines - Implementing Replacement, Reduction and Refinement: Challenges and Priorities". This conference was organized by the International Alliance for Biological Standardization (IABS), and held in Bangkok, Thailand on December 3 and 4 2019. Participants comprised stakeholders from many parts of the world, including vaccine developers, manufacturers and regulators from Asia, Europe, North America, Australia and New Zealand. In interactive workshops and vibrant panel discussions, the attendees worked together to identify the remaining barriers to validation, acceptance and implementation of alternative methods, and how harmonization could be promoted, especially for LMICs.
  • |Animal Testing Alternatives/*methods/standards[MESH]
  • |Animal Welfare/standards[MESH]
  • |Animals[MESH]
  • |Humans[MESH]
  • |Quality Control[MESH]
  • |Vaccination/*methods[MESH]


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