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10.1016/j.ajem.2020.08.025 http://scihub22266oqcxt.onion/10.1016/j.ajem.2020.08.025 33041110!7438273!33041110     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33041110&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Am+J+Emerg+Med 2021 ; 45 (?): 179-184 Nephropedia Template TP {{tp|p=33041110|t=2021. Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis |pdf=|usr=}}{{33041110}} gab.com Text Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis JO: Am J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=33041110 #FOAvip BACKGROUND: Coronavirus disease 2019 (COVID-19) is a rapidly escalating pandemic that has spread to many parts of the world. As such, there is urgent need to identify predictors of clinical severity in COVID-19 patients. This may be useful for early identification of patients who may require life-saving interventions. In this meta-analysis, we evaluated whether malignancies are associated with a significantly enhanced odds of COVID-19 severity and mortality. METHOD: A systematic search of literature was conducted between November 1, 2019, to May 26th, 2020 on PubMed and China National Knowledge Infrastructure (CNKI) to identify studies reporting data on cancers in patients with or without severe COVID-19 were included. The primary outcome of interest was the association between malignancies and COVID-19 severity, while the secondary outcome was the association between malignancies and COVID-19 mortality. Data were pooled into a meta-analysis to estimate pooled odds ratio (OR) with 95% confidence interval (95% CI) for either outcome. RESULTS: A total of 20 studies (n = 4549 patients) were included. Overall, malignancies were found to be associated with significantly increased odds of COVID-19 severity (OR = 2.17; 95% CI 1.47-3.196; p < 0.001) and mortality (OR = 2.39; 95% CI 1.18-4.85; p = 0.016). No heterogeneity was observed for both outcomes (Cochran's Q = 6.558, p = 0.922, I(2) = 0% and Cochran's Q = 2.91, p = 0.71, I(2) = 0% respectively). CONCLUSION: Malignancies were significantly associated with a 2-fold increase in the odds of developing severe COVID-19 disease, as well as mortality. Larger studies are needed to corroborate these findings. These patients should be closely monitored for any signs of unfavorable disease progression. Twit Text FOAVip Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis ????Am J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=33041110 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33041110 #FOAvip English Wikipedia <ref>{{Cite pmid|33041110}}</ref> Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis #MMPMID33041110 Cheruiyot I; Kipkorir V; Ngure B; Misiani M; Munguti J Am J Emerg Med 2021[Jul]; 45 (?): 179-184 PMID33041110show ga BACKGROUND: Coronavirus disease 2019 (COVID-19) is a rapidly escalating pandemic that has spread to many parts of the world. As such, there is urgent need to identify predictors of clinical severity in COVID-19 patients. This may be useful for early identification of patients who may require life-saving interventions. In this meta-analysis, we evaluated whether malignancies are associated with a significantly enhanced odds of COVID-19 severity and mortality. METHOD: A systematic search of literature was conducted between November 1, 2019, to May 26th, 2020 on PubMed and China National Knowledge Infrastructure (CNKI) to identify studies reporting data on cancers in patients with or without severe COVID-19 were included. The primary outcome of interest was the association between malignancies and COVID-19 severity, while the secondary outcome was the association between malignancies and COVID-19 mortality. Data were pooled into a meta-analysis to estimate pooled odds ratio (OR) with 95% confidence interval (95% CI) for either outcome. RESULTS: A total of 20 studies (n = 4549 patients) were included. Overall, malignancies were found to be associated with significantly increased odds of COVID-19 severity (OR = 2.17; 95% CI 1.47-3.196; p < 0.001) and mortality (OR = 2.39; 95% CI 1.18-4.85; p = 0.016). No heterogeneity was observed for both outcomes (Cochran's Q = 6.558, p = 0.922, I(2) = 0% and Cochran's Q = 2.91, p = 0.71, I(2) = 0% respectively). CONCLUSION: Malignancies were significantly associated with a 2-fold increase in the odds of developing severe COVID-19 disease, as well as mortality. Larger studies are needed to corroborate these findings. These patients should be closely monitored for any signs of unfavorable disease progression. |*Pandemics[MESH] |COVID-19/*epidemiology[MESH] |Comorbidity[MESH] |Global Health[MESH] |Humans[MESH] |Neoplasms/*epidemiology[MESH] |Risk Assessment/*methods[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]Cancer is associated with coronavirus disease (COVID-19) severity and (epmc).pdf DeepDyve Pubget Overpricing