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10.1016/j.dsx.2020.10.001 http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.10.001 33039937!7536590!33039937     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diabetes+Metab+Syndr 2020 ; 14 (6): 1951-1954 Nephropedia Template TP {{tp|p=33039937|t=2020. Pattern of liver function and clinical profile in COVID-19: A cross-sectional study of 91 patients |pdf=|usr=}}{{33039937}} gab.com Text Pattern of liver function and clinical profile in COVID-19: A cross-sectional study of 91 patients JO: Diabetes Metab Syndr http://www.kidney.de/pget.php?&tw=1&pmid=33039937 #FOAvip BACKGROUND: - COVID-19 caused by SARS-CoV-2 leads to myriad range of organ involvement including liver dysfunction. AIM: To analyse the liver function in patients with COVID-19 and their association with respect to age, sex, severity of disease and clinical features. MATERIALS AND METHODS: This study was a cross-sectional study done at Rajendra Institute of Medical Sciences, Ranchi. 91 patients admitted with confirmed SARS-CoV-2 infection were included in this study and divided into asymptomatic, mild, moderate and severe groups. Liver function tests were compared among different severity groups. RESULTS: Of 91 patients with COVID-19, 70 (76.9%) had abnormal liver function. Aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin levels was 1-2 x ULN in 33(36.3%), 34(37.3%), 12(13.2%), 6(6.6%) cases and >2 x ULN in 20(22%), 18(19.8%), 7(7.7%) and 2 (2.2%) cases respectively. Mean AST and ALP levels among different severity groups of COVID-19 was statistically significant (p < 0.05) whereas mean ALT and total bilirubin levels was statistically non-significant (p > 0.05). There was no statistical difference between males and females with regard to abnormal liver function. Liver injury was seen in 64.3% cases of hypertension and 73.3% cases of diabetes. Fever, myalgia, headache and breathlessness were found to be correlated significantly with severity of disease. CONCLUSION: Liver injury is common in SARS-CoV-2 infection and is more prevalent in the severe disease group. Aspartate transaminase and alkaline phosphatase are better indicators of covid-19 induced liver injury than alanine transaminase and total bilirubin. Twit Text FOAVip Pattern of liver function and clinical profile in COVID-19: A cross-sectional study of 91 patients ????Diabetes Metab Syndr http://www.kidney.de/pget.php?&tw=1&pmid=33039937 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33039937 #FOAvip English Wikipedia <ref>{{Cite pmid|33039937}}</ref> Pattern of liver function and clinical profile in COVID-19: A cross-sectional study of 91 patients #MMPMID33039937 Kumar A; Kumar P; Dungdung A; Kumar Gupta A; Anurag A; Kumar A Diabetes Metab Syndr 2020[Nov]; 14 (6): 1951-1954 PMID33039937show ga BACKGROUND: - COVID-19 caused by SARS-CoV-2 leads to myriad range of organ involvement including liver dysfunction. AIM: To analyse the liver function in patients with COVID-19 and their association with respect to age, sex, severity of disease and clinical features. MATERIALS AND METHODS: This study was a cross-sectional study done at Rajendra Institute of Medical Sciences, Ranchi. 91 patients admitted with confirmed SARS-CoV-2 infection were included in this study and divided into asymptomatic, mild, moderate and severe groups. Liver function tests were compared among different severity groups. RESULTS: Of 91 patients with COVID-19, 70 (76.9%) had abnormal liver function. Aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin levels was 1-2 x ULN in 33(36.3%), 34(37.3%), 12(13.2%), 6(6.6%) cases and >2 x ULN in 20(22%), 18(19.8%), 7(7.7%) and 2 (2.2%) cases respectively. Mean AST and ALP levels among different severity groups of COVID-19 was statistically significant (p < 0.05) whereas mean ALT and total bilirubin levels was statistically non-significant (p > 0.05). There was no statistical difference between males and females with regard to abnormal liver function. Liver injury was seen in 64.3% cases of hypertension and 73.3% cases of diabetes. Fever, myalgia, headache and breathlessness were found to be correlated significantly with severity of disease. CONCLUSION: Liver injury is common in SARS-CoV-2 infection and is more prevalent in the severe disease group. Aspartate transaminase and alkaline phosphatase are better indicators of covid-19 induced liver injury than alanine transaminase and total bilirubin. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Alanine Transaminase/blood[MESH] |Alkaline Phosphatase/blood[MESH] |Aspartate Aminotransferases/blood[MESH] |Bilirubin/blood[MESH] |COVID-19/*blood/complications[MESH] |Cross-Sectional Studies[MESH] |Diabetes Complications/blood[MESH] |Diabetes Mellitus/blood[MESH] |Female[MESH] |Humans[MESH] |Hypertension/blood/complications[MESH] |India[MESH] |Liver Diseases/*blood/etiology[MESH] |Male[MESH] |Middle Aged[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]Pattern of liver function and clinical profile in COVID-19: A cross-se(epmc).pdf DeepDyve Pubget Overpricing