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10.1016/j.athoracsur.2020.08.007

http://scihub22266oqcxt.onion/10.1016/j.athoracsur.2020.08.007
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33038341!7543779!33038341
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suck abstract from ncbi


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pmid33038341      Ann+Thorac+Surg 2021 ; 111 (5): 1682-1688
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  • Maintaining Surgical Treatment of Non-Small Cell Lung Cancer During the COVID-19 Pandemic in Paris #MMPMID33038341
  • Leclere JB; Fournel L; Etienne H; Al Zreibi C; Onorati I; Roussel A; Castier Y; Martinod E; Le Pimpec-Barthes F; Alifano M; Assouad J; Mordant P
  • Ann Thorac Surg 2021[May]; 111 (5): 1682-1688 PMID33038341show ga
  • BACKGROUND: The coronavirus disease 2019 (COVID-19) outbreak was officially declared in France on March 14, 2020. The objective of this study is to report the incidence and outcome of COVID-19 after surgical resection of non-small cell lung cancer in Paris Public Hospitals during the pandemic. METHODS: We retrospective analyzed a prospective database including all patients who underwent non-small cell lung cancer resection between March 14, 2020, and May 11, 2020, in the 5 thoracic surgery units of Paris Public Hospitals. The primary endpoint was the occurrence of SARS-CoV-2 infection during the first 30 days after surgery. RESULTS: Study group included 115 patients (male 57%, age 64.6 +/- 10.7 years, adenocarcinoma 66%, cT1 62%, cN0 82%). During the first month after surgery, 6 patients (5%) were diagnosed with COVID-19. As compared with COVID-negative patients, COVID-positive patients were more likely to be operated on during the first month of the pandemic (100% vs 54%, P = .03) and to be on corticosteroids preoperatively (33% vs 4%, P = .03). Postoperative COVID-19 was associated with an increased rate of readmission (50% vs 5%, P = .004), but no difference in 30-day morbidity (for the study group: grade 2, 24%; grade 3, 7%; grade 4, 1%) or mortality (n = 1 COVID-negative patient, 0.9%). Immediate oncologic outcomes did not differ significantly between groups (R0 resection 99%, nodal upstaging 14%, adjuvant chemotherapy 29%). CONCLUSIONS: During the COVID-19 pandemic, surgical treatment of non-small cell lung cancer was associated with a rate of postoperative COVID-19 of 5% with a significant impact on readmissions but not on other outcomes studied.
  • |*Pandemics/statistics & numerical data[MESH]
  • |Aged[MESH]
  • |COVID-19/*epidemiology/etiology/virology[MESH]
  • |Carcinoma, Non-Small-Cell Lung/epidemiology/*surgery[MESH]
  • |Female[MESH]
  • |France/epidemiology[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Lung Neoplasms/epidemiology/*surgery[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Patient Readmission/statistics & numerical data[MESH]
  • |Pneumonectomy/*adverse effects/statistics & numerical data[MESH]
  • |Retrospective Studies[MESH]


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