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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Clin+Biochem 2020 ; 86 (ä): 1-7 Nephropedia Template TP
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Canadian society of clinical chemists (CSCC) interim consensus guidance for testing and reporting of SARS-CoV-2 serology #MMPMID33031819
Bailey D; Konforte D; Barakauskas VE; Yip PM; Kulasingam V; Abou El Hassan M; Beach LA; Blasutig IM; Catomeris P; Dooley KC; Gong Y; Kavsak P; Randell EW; Robinson JL; Shaw J; Taher J; White-Al Habeeb N
Clin Biochem 2020[Dec]; 86 (ä): 1-7 PMID33031819show ga
Clinical laboratories across the world are working to validate and perform testing for SARS-CoV-2 antibodies. Herein, we present interim consensus guidance for Canadian clinical laboratories testing and reporting SARS-CoV-2 serology, with emphasis on the capabilities and limitations of these tests and recommendations for interpretative comments in an effort to achieve harmonized laboratory practices. The consensus document provides a broad overview of topics including sample type and contamination risk; kinetics of antibody response to COVID-19 and the impact on serology testing; clinical utility of SARS-CoV-2 serology testing; clinical performance of commercial laboratory-based assays commonly deployed in North America; recommendations for interim reporting; utility of SARS-CoV-2 antibody testing for pediatric patients; and utility of point-of-care testing. The information is based on the current literature and is subject to change as additional information becomes available.