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Mining the Antibody Repertoire for Solutions to SARS-CoV-2 #MMPMID33031765
Meng W; Rosenfeld AM; Luning Prak ET
Cell Host Microbe 2020[Oct]; 28 (4): 499-501 PMID33031765show ga
In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing.