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10.1089/pop.2020.0230

http://scihub22266oqcxt.onion/10.1089/pop.2020.0230
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33031013!7875135!33031013
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suck abstract from ncbi


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pmid33031013      Popul+Health+Manag 2021 ; 24 (S1): S43-S51
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  • The Opioid Epidemic Within the COVID-19 Pandemic: Drug Testing in 2020 #MMPMID33031013
  • Niles JK; Gudin J; Radcliff J; Kaufman HW
  • Popul Health Manag 2021[Feb]; 24 (S1): S43-S51 PMID33031013show ga
  • The convergence of the opioid epidemic and the coronavirus disease 2019 (COVID-19) pandemic has created new health care challenges. The authors analyzed changes in clinical drug testing patterns and results at a national clinical laboratory, comparing data obtained before and during the pandemic. Testing for prescription and illicit drugs declined rapidly during the pandemic, with weekly test volumes falling by approximately 70% from the baseline period to the trough (the week beginning March 29) before rising in subsequent weeks. Among individuals tested, positivity increased by 35% for non-prescribed fentanyl and 44% for heroin during the pandemic. Positivity for non-prescribed fentanyl increased significantly among patients positive for other drugs: by 89% for specimens positive for amphetamines; 48% for benzodiazepines; 34% for cocaine; and 39% for opiates (P < 0.01 for all comparisons). These findings suggest significant increases in dangerous drug combinations. Positivity for non-prescribed use of many other drugs remained consistent or declined for some drugs, relative to pre-pandemic patterns. Models adjusting for potential confounding variables, including medication-assisted treatment and treatment at a substance use disorder facility indicated that the risk for non-prescribed fentanyl positivity rose by more than 50% during the pandemic. In summary, these findings demonstrate decreased drug testing overall, with increased positivity for high-risk drugs and dangerous drug combinations. The convergence of the drug abuse epidemic and COVID-19 pandemic has led to an increased need for health care and public health resources dedicated to supporting vulnerable patients and addressing the underlying causes of these disturbing trends.
  • |*COVID-19[MESH]
  • |*Opioid-Related Disorders/diagnosis/epidemiology[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Analgesics, Opioid/urine[MESH]
  • |Female[MESH]
  • |Fentanyl/urine[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Opioid Epidemic/*statistics & numerical data[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]
  • |Substance Abuse Detection/*statistics & numerical data[MESH]
  • |Substance-Related Disorders/diagnosis/epidemiology[MESH]


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