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10.3390/jcm9103207 http://scihub22266oqcxt.onion/10.3390/jcm9103207 33027886!7599850!33027886     free     free     free       J+Clin+Med 2020 ; 9 (10): ä Nephropedia Template TP {{tp|p=33027886|t=2020. Hypercapnia: An Aggravating Factor in Asthma |pdf=|usr=}}{{33027886}} gab.com Text Hypercapnia: An Aggravating Factor in Asthma JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=33027886 #FOAvip Asthma is a common chronic respiratory disorder with relatively good outcomes in the majority of patients with appropriate maintenance therapy. However, in a small minority, patients can experience severe asthma with respiratory failure and hypercapnia, necessitating intensive care unit admission. Hypercapnia occurs due to alveolar hypoventilation and insufficient removal of carbon dioxide (CO(2)) from the blood. Although mild hypercapnia is generally well tolerated in patients with asthma, there is accumulating evidence that elevated levels of CO(2) can act as a gaso-signaling molecule, triggering deleterious effects in various organs such as the lung, skeletal muscles and the innate immune system. Here, we review recent advances on pathophysiological response to hypercapnia and discuss potential detrimental effects of hypercapnia in patients with asthma. Twit Text FOAVip Hypercapnia: An Aggravating Factor in Asthma ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=33027886 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33027886 #FOAvip English Wikipedia <ref>{{Cite pmid|33027886}}</ref> Hypercapnia: An Aggravating Factor in Asthma #MMPMID33027886 Shigemura M; Homma T; Sznajder JI J Clin Med 2020[Oct]; 9 (10): ä PMID33027886show ga Asthma is a common chronic respiratory disorder with relatively good outcomes in the majority of patients with appropriate maintenance therapy. However, in a small minority, patients can experience severe asthma with respiratory failure and hypercapnia, necessitating intensive care unit admission. Hypercapnia occurs due to alveolar hypoventilation and insufficient removal of carbon dioxide (CO(2)) from the blood. Although mild hypercapnia is generally well tolerated in patients with asthma, there is accumulating evidence that elevated levels of CO(2) can act as a gaso-signaling molecule, triggering deleterious effects in various organs such as the lung, skeletal muscles and the innate immune system. Here, we review recent advances on pathophysiological response to hypercapnia and discuss potential detrimental effects of hypercapnia in patients with asthma. äHypercapnia: An Aggravating Factor in Asthma (epmc).pdf DeepDyve Pubget Overpricing