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10.1007/s00705-020-04830-0

http://scihub22266oqcxt.onion/10.1007/s00705-020-04830-0
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33025199!7538173!33025199
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suck abstract from ncbi


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pmid33025199      Arch+Virol 2020 ; 165 (12): 2937-2944
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  • Identification of novel mutations in SARS-COV-2 isolates from Turkey #MMPMID33025199
  • Rehman S; Mahmood T; Aziz E; Batool R
  • Arch Virol 2020[Dec]; 165 (12): 2937-2944 PMID33025199show ga
  • SARS-CoV-2 was first detected in the city of Wuhan, Hubei Province, China. In this study, we identified 11 unique mutations in viral SARS-COV-2 isolates from Turkey. Nine of them cause structural alterations in the S protein, nsp2, nsp3, nsp4 and nsp12 regions. The mutations identified here might have significant functional implications that need to be addressed in future studies in the context of vaccine engineering and therapeutic interventions. Moreover, transmission and phylogenetic analysis revealed multiple independent sources of introductions of SARS-CoV-2 into Turkey and a close relationship to the isolates from Saudi Arabia.
  • |*Pandemics[MESH]
  • |*Point Mutation[MESH]
  • |Amino Acid Sequence[MESH]
  • |Amino Acid Substitution[MESH]
  • |Betacoronavirus/classification/*genetics/isolation & purification/pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Coronavirus Infections/*diagnosis/*epidemiology/transmission/virology[MESH]
  • |Humans[MESH]
  • |Phylogeny[MESH]
  • |Pneumonia, Viral/*diagnosis/*epidemiology/transmission/virology[MESH]
  • |SARS-CoV-2[MESH]
  • |Sequence Alignment[MESH]
  • |Sequence Homology, Amino Acid[MESH]
  • |Spike Glycoprotein, Coronavirus/*genetics[MESH]


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