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10.1016/j.jiac.2020.09.008

http://scihub22266oqcxt.onion/10.1016/j.jiac.2020.09.008
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33023821!7834326!33023821
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suck abstract from ncbi


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pmid33023821      J+Infect+Chemother 2021 ; 27 (1): 99-102
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  • COVID-19 outbreak in Italy: Clinical-radiological presentation and outcome in three oncologic patients #MMPMID33023821
  • Colombi D; Bodini FC; Morelli N; Silva M; Milanese G; Cavanna L; Michieletti E
  • J Infect Chemother 2021[Jan]; 27 (1): 99-102 PMID33023821show ga
  • We present three patients affected by pulmonary squamous cell carcinoma, metastatic esophageal cancer and advanced non-Hodgkin lymphoma, who incurred in coronavirus 2019 (COVID-19) infection during the early phase of epidemic wave in Italy. All patients presented with fever. Social contact with subject positive for COVID-19 was declared in only one of the three cases. In all cases, laboratory findings showed lymphopenia and elevated C-reactive protein (CRP). Chest x-ray and computed tomography showed bilateral ground-glass opacities, shadowing, interstitial abnormalities, and "crazy paving" pattern which evolved with superimposition of consolidations in one patient. All patients received antiviral therapy based on ritonavir and lopinavir, associated with hydroxychloroquine. Despite treatment, two patients with advanced cancers died after 39 and 17 days of hospitalization, while the patient with lung cancer was dismissed at home, in good conditions.
  • |Aged[MESH]
  • |Anti-Bacterial Agents/therapeutic use[MESH]
  • |Antiviral Agents/therapeutic use[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Carcinoma, Squamous Cell/complications/diagnosis/drug therapy[MESH]
  • |Coronavirus Infections/complications/diagnosis/*drug therapy[MESH]
  • |Disease Outbreaks[MESH]
  • |Drug Therapy, Combination[MESH]
  • |Esophageal Neoplasms/complications/diagnosis/drug therapy[MESH]
  • |Fatal Outcome[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/*therapeutic use[MESH]
  • |Italy[MESH]
  • |Lopinavir/*therapeutic use[MESH]
  • |Lung Neoplasms/complications/diagnosis/drug therapy[MESH]
  • |Lymphoma, Non-Hodgkin/complications/diagnosis/drug therapy[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neoplasms/*complications/diagnosis/drug therapy[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*drug therapy[MESH]
  • |Ritonavir/*therapeutic use[MESH]
  • |SARS-CoV-2[MESH]
  • |Tomography, X-Ray Computed[MESH]


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