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10.3390/ijms21197310

http://scihub22266oqcxt.onion/10.3390/ijms21197310
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33022979!7582686!33022979
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suck abstract from ncbi


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pmid33022979      Int+J+Mol+Sci 2020 ; 21 (19): ä
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  • Susceptibility Factors in Chronic Lung Inflammatory Responses to Engineered Nanomaterials #MMPMID33022979
  • You DJ; Bonner JC
  • Int J Mol Sci 2020[Oct]; 21 (19): ä PMID33022979show ga
  • Engineered nanomaterials (ENMs) are products of the emerging nanotechnology industry and many different types of ENMs have been shown to cause chronic inflammation in the lungs of rodents after inhalation exposure, suggesting a risk to human health. Due to the increasing demand and use of ENMs in a variety of products, a careful evaluation of the risks to human health is urgently needed. An assessment of the immunotoxicity of ENMs should consider susceptibility factors including sex, pre-existing diseases, deficiency of specific genes encoding proteins involved in the innate or adaptive immune response, and co-exposures to other chemicals. This review will address evidence from experimental animal models that highlights some important issues of susceptibility to chronic lung inflammation and systemic immune dysfunction after pulmonary exposure to ENMs.
  • |Animals[MESH]
  • |Humans[MESH]
  • |Inflammation/chemically induced/complications/*pathology[MESH]
  • |Inhalation Exposure[MESH]
  • |Lung/*drug effects/pathology[MESH]
  • |Nanostructures/*adverse effects/therapeutic use[MESH]


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