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10.1097/SLA.0000000000004218

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suck abstract from ncbi


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pmid33021367      Ann+Surg 2020 ; 272 (6): 919-924
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  • Yield of Screening for COVID-19 in Asymptomatic Patients Before Elective or Emergency Surgery Using Chest CT and RT-PCR (SCOUT): Multicenter Study #MMPMID33021367
  • Puylaert CAJ; Scheijmans JCG; Borgstein ABJ; Andeweg CS; Bartels-Rutten A; Beets GL; van Berge Henegouwen MI; Braak SJ; Couvreur R; Daams F; van Es HW; Franken LC; Grotenhuis BA; Hendriks ER; de Hingh IHJT; Hoeijmakers F; Ten Holder JT; Huisman PM; Kazemier G; van Kesteren F; van Kesteren J; Keywani K; Kuiper SZ; Lange MDJ; Lobatto ME; du Mee AWF; Poeze M; van Praag EM; van Rossen J; van Santvoort HC; Sedee WJA; Seelen LWF; Sharabiany S; Sosef NL; Quanjel MJR; Veltman J; Verhagen T; van de Vlasakker VCJ; Weeder PD; van Werven JR; Wesdorp NJ; van Dieren S; Han AX; Russell CA; de Jong MD; Bossuyt PMM; Quarles van Ufford JME; Prokop MW; Gisbertz SS; Prins JM; Besselink MG; Boermeester MA; Gietema HA; Stoker J
  • Ann Surg 2020[Dec]; 272 (6): 919-924 PMID33021367show ga
  • OBJECTIVE: To determine the yield of preoperative screening for COVID-19 with chest CT and RT-PCR in patients without COVID-19 symptoms. SUMMARY OF BACKGROUND DATA: Many centers are currently screening surgical patients for COVID-19 using either chest CT, RT-PCR or both, due to the risk for worsened surgical outcomes and nosocomial spread. The optimal design and yield of such a strategy are currently unknown. METHODS: This multicenter study included consecutive adult patients without COVID-19 symptoms who underwent preoperative screening using chest CT and RT-PCR before elective or emergency surgery under general anesthesia. RESULTS: A total of 2093 patients without COVID-19 symptoms were included in 14 participating centers; 1224 were screened by CT and RT-PCR and 869 by chest CT only. The positive yield of screening using a combination of chest CT and RT-PCR was 1.5% [95% confidence interval (CI): 0.8-2.1]. Individual yields were 0.7% (95% CI: 0.2-1.1) for chest CT and 1.1% (95% CI: 0.6-1.7) for RT-PCR; the incremental yield of chest CT was 0.4%. In relation to COVID-19 community prevalence, up to approximately 6% positive RT-PCR was found for a daily hospital admission rate >1.5 per 100,000 inhabitants, and around 1.0% for lower prevalence. CONCLUSIONS: One in every 100 patients without COVID-19 symptoms tested positive for SARS-CoV-2 with RT-PCR; this yield increased in conjunction with community prevalence. The added value of chest CT was limited. Preoperative screening allowed us to take adequate precautions for SARS-CoV-2 positive patients in a surgical population, whereas negative patients needed only routine procedures.
  • |*Asymptomatic Infections[MESH]
  • |*Emergency Treatment[MESH]
  • |*Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |*SARS-CoV-2[MESH]
  • |*Surgical Procedures, Operative[MESH]
  • |*Tomography, X-Ray Computed[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |Elective Surgical Procedures[MESH]
  • |Humans[MESH]
  • |Mass Screening/*statistics & numerical data[MESH]
  • |Preoperative Care/*methods[MESH]
  • |Retrospective Studies[MESH]


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