Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.2174/1573397116666201005122603 http://scihub22266oqcxt.onion/10.2174/1573397116666201005122603 33019935!ä!33019935 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Rheumatol+Rev 2021 ; 17 (1): 7-16 Nephropedia Template TP {{tp|p=33019935|t=2021. COVID-19: A Great Mime or a Trigger Event of Autoimmune Manifestations?|pdf=|usr=}}{{33019935}} gab.com Text COVID-19: A Great Mime or a Trigger Event of Autoimmune Manifestations JO: Curr Rheumatol Rev http://www.kidney.de/pget.php?&tw=1&pmid=33019935 #FOAvip Viruses can induce autoimmune diseases, in addition to genetic predisposition and environmental factors. Particularly, coronaviruses are mentioned among the viruses implicated in autoimmunity. Today, the world's greatest threat derives from the pandemic of a new human coronavirus, called "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the responsible agent of coronavirus disease 2019 (COVID-19). First case of COVID-19 was identified in Wuhan, the capital of Hubei, China, in December 2019 and quickly spread around the world. This review focuses on autoimmune manifestations described during COVID-19, including pro-thrombotic state associated with antiphospholipid antibodies (aPL), acute interstitial pneumonia, macrophage activation syndrome, lymphocytopenia, systemic vasculitis, and autoimmune skin lesions. This offers the opportunity to highlight the pathogenetic mechanisms common to COVID-19 and several autoimmune diseases in order to identify new therapeutic targets. In a supposed preliminary pathogenetic model, SARS-CoV-2 plays a direct role in triggering widespread microthrombosis and microvascular inflammation, because it is able to induce transient aPL, endothelial damage and complement activation at the same time. Hence, endothelium might represent the common pathway in which autoimmunity and infection converge. In addition, autoimmune phenomena in COVID-19 can be explained by regulatory T cells impairment and cytokines cascade. Twit Text FOAVip COVID-19: A Great Mime or a Trigger Event of Autoimmune Manifestations ????Curr Rheumatol Rev http://www.kidney.de/pget.php?&tw=1&pmid=33019935 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33019935 #FOAvip English Wikipedia <ref>{{Cite pmid|33019935}}</ref> COVID-19: A Great Mime or a Trigger Event of Autoimmune Manifestations? #MMPMID33019935 Fatone MC Curr Rheumatol Rev 2021[]; 17 (1): 7-16 PMID33019935show ga Viruses can induce autoimmune diseases, in addition to genetic predisposition and environmental factors. Particularly, coronaviruses are mentioned among the viruses implicated in autoimmunity. Today, the world's greatest threat derives from the pandemic of a new human coronavirus, called "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the responsible agent of coronavirus disease 2019 (COVID-19). First case of COVID-19 was identified in Wuhan, the capital of Hubei, China, in December 2019 and quickly spread around the world. This review focuses on autoimmune manifestations described during COVID-19, including pro-thrombotic state associated with antiphospholipid antibodies (aPL), acute interstitial pneumonia, macrophage activation syndrome, lymphocytopenia, systemic vasculitis, and autoimmune skin lesions. This offers the opportunity to highlight the pathogenetic mechanisms common to COVID-19 and several autoimmune diseases in order to identify new therapeutic targets. In a supposed preliminary pathogenetic model, SARS-CoV-2 plays a direct role in triggering widespread microthrombosis and microvascular inflammation, because it is able to induce transient aPL, endothelial damage and complement activation at the same time. Hence, endothelium might represent the common pathway in which autoimmunity and infection converge. In addition, autoimmune phenomena in COVID-19 can be explained by regulatory T cells impairment and cytokines cascade. |Animals[MESH] |Antibodies, Antiphospholipid/immunology/metabolism[MESH] |Autoimmune Diseases/etiology/*immunology/metabolism[MESH] |Autoimmunity/*physiology[MESH] |COVID-19/complications/*immunology/metabolism[MESH] |Cytokines/immunology/metabolism[MESH] |Humans[MESH] |Inflammation/etiology/immunology/metabolism[MESH] |Macrophage Activation/physiology[MESH]COVID-19: A Great Mime or a Trigger Event of Autoimmune Manifestations(epmc).pdf DeepDyve Pubget Overpricing