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10.1002/ppul.25106

http://scihub22266oqcxt.onion/10.1002/ppul.25106
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33017102!7675606!33017102
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suck abstract from ncbi


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pmid33017102      Pediatr+Pulmonol 2020 ; 55 (12): 3595-3601
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  • Is vitamin D deficiency a risk factor for COVID-19 in children? #MMPMID33017102
  • Yilmaz K; Sen V
  • Pediatr Pulmonol 2020[Dec]; 55 (12): 3595-3601 PMID33017102show ga
  • OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a global health problem that can result in serious complications. The aim of this study was to investigate the prevalence and clinical importance of vitamin D deficiency in children with COVID-19. MATERIAL AND METHODS: This study includes 40 patients who were diagnosed to have COVID-19 and hospitalized with the real-time reverse transcription polymerase chain reaction method, 45 healthy matched control subjects with vitamin D levels. The age of admission, clinical and laboratory data, and 25-hydroxycholecalciferol (25-OHD) levels were recorded. Those with vitamin D levels which are below 20 ng/ml were determined as Group 1 and those with >/=20 ng/ml as Group 2. RESULTS: Patients with COVID-19 had significantly lower vitamin D levels 13.14 mug/L (4.19-69.28) than did the controls 34.81 (3.8-77.42) mug/L (p < .001). Patients with COVID-19 also had significantly lower serum phosphorus (4.09 +/- 0.73 vs. 5.06 +/- 0.93 vs. (U/L) (p < .001)) values compared with the controls. The symptom of fever was significantly higher in COVID- 19 patients who had deficient and insufficient vitamin D levels than in patients who had sufficient vitamin D levels (p = .038). There was a negative correlation found between fever symptom and vitamin D level (r = -0.358, p = .023). CONCLUSION: This is the first to evaluate vitamin D levels and its relationship with clinical findings in pediatric patients with COVID-19. Our results suggest that vitamin D values may be associated with the occurrence and management of the COVID-19 disease by modulating the immunological mechanism to the virus in the pediatric population.
  • |Adolescent[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Calcifediol/*blood[MESH]
  • |Case-Control Studies[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Coronavirus[MESH]
  • |Coronavirus Infections/blood/*epidemiology/physiopathology[MESH]
  • |Female[MESH]
  • |Fever/physiopathology[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Phosphorus/blood[MESH]
  • |Pneumonia, Viral/blood/*epidemiology/physiopathology[MESH]
  • |Prevalence[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Turkey/epidemiology[MESH]
  • |Vitamin D Deficiency/blood/*epidemiology[MESH]
  • |Vitamin D/blood[MESH]


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