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10.1016/j.xcrm.2020.100126 http://scihub22266oqcxt.onion/10.1016/j.xcrm.2020.100126 33015650!7524645!33015650     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep+Med 2020 ; 1 (7): 100126 Nephropedia Template TP {{tp|p=33015650|t=2020. Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike |pdf=|usr=}}{{33015650}} gab.com Text Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike JO: Cell Rep Med http://www.kidney.de/pget.php?&tw=1&pmid=33015650 #FOAvip SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. The Spike glycoproteins of SARS-CoV-2 mediate viral entry and are the main targets for neutralizing antibodies. Understanding the antibody response directed against SARS-CoV-2 is crucial for the development of vaccine, therapeutic, and public health interventions. Here, we perform a cross-sectional study on 106 SARS-CoV-2-infected individuals to evaluate humoral responses against SARS-CoV-2 Spike. Most infected individuals elicit anti-Spike antibodies within 2 weeks of the onset of symptoms. The levels of receptor binding domain (RBD)-specific immunoglobulin G (IgG) persist over time, and the levels of anti-RBD IgM decrease after symptom resolution. Although most individuals develop neutralizing antibodies within 2 weeks of infection, the level of neutralizing activity is significantly decreased over time. Our results highlight the importance of studying the persistence of neutralizing activity upon natural SARS-CoV-2 infection. Twit Text FOAVip Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike ????Cell Rep Med http://www.kidney.de/pget.php?&tw=1&pmid=33015650 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33015650 #FOAvip English Wikipedia <ref>{{Cite pmid|33015650}}</ref> Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike #MMPMID33015650 Prevost J; Gasser R; Beaudoin-Bussieres G; Richard J; Duerr R; Laumaea A; Anand SP; Goyette G; Benlarbi M; Ding S; Medjahed H; Lewin A; Perreault J; Tremblay T; Gendron-Lepage G; Gauthier N; Carrier M; Marcoux D; Piche A; Lavoie M; Benoit A; Loungnarath V; Brochu G; Haddad E; Stacey HD; Miller MS; Desforges M; Talbot PJ; Maule GTG; Cote M; Therrien C; Serhir B; Bazin R; Roger M; Finzi A Cell Rep Med 2020[Oct]; 1 (7): 100126 PMID33015650show ga SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. The Spike glycoproteins of SARS-CoV-2 mediate viral entry and are the main targets for neutralizing antibodies. Understanding the antibody response directed against SARS-CoV-2 is crucial for the development of vaccine, therapeutic, and public health interventions. Here, we perform a cross-sectional study on 106 SARS-CoV-2-infected individuals to evaluate humoral responses against SARS-CoV-2 Spike. Most infected individuals elicit anti-Spike antibodies within 2 weeks of the onset of symptoms. The levels of receptor binding domain (RBD)-specific immunoglobulin G (IgG) persist over time, and the levels of anti-RBD IgM decrease after symptom resolution. Although most individuals develop neutralizing antibodies within 2 weeks of infection, the level of neutralizing activity is significantly decreased over time. Our results highlight the importance of studying the persistence of neutralizing activity upon natural SARS-CoV-2 infection. äCross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spi(epmc).pdf DeepDyve Pubget Overpricing