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10.1063/5.0021842

http://scihub22266oqcxt.onion/10.1063/5.0021842
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33012808!7518548!33012808
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suck abstract from ncbi


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pmid33012808      Appl+Phys+Lett 2020 ; 117 (12): 120601
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  • Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2 #MMPMID33012808
  • Peng T; Liu X; Adams LG; Agarwal G; Akey B; Cirillo J; Deckert V; Delfan S; Fry E; Han Z; Hemmer P; Kattawar G; Kim M; Lee MC; Lu C; Mogford J; Nessler R; Neuman B; Nie X; Pan J; Pryor J; Rajil N; Shih Y; Sokolov A; Svidzinsky A; Wang D; Yi Z; Zheltikov A; Scully M
  • Appl Phys Lett 2020[Sep]; 117 (12): 120601 PMID33012808show ga
  • Lateral flow assay (LFA) has long been used as a biomarker detection technique. It has advantages such as low cost, rapid readout, portability, and ease of use. However, its qualitative readout process and lack of sensitivity are limiting factors. We report a photon-counting approach to accurately quantify LFAs while enhancing sensitivity. In particular, we demonstrate that the density of SARS-CoV-2 antibodies can be quantified and measured with an enhanced sensitivity using this simple laser optical analysis.
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