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10.1136/bcr-2020-239015

http://scihub22266oqcxt.onion/10.1136/bcr-2020-239015
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33012721!7536775!33012721
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suck abstract from ncbi

pmid33012721      BMJ+Case+Rep 2020 ; 13 (10): ?
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  • Non-convulsive status epilepticus: COVID-19 or clozapine induced? #MMPMID33012721
  • Sokolov E; Hadavi S; Mantoan Ritter L; Brunnhuber F
  • BMJ Case Rep 2020[Oct]; 13 (10): ? PMID33012721show ga
  • We present a case of non-convulsive status epilepticus in a 57-year-old woman with a schizoaffective disorder, without an antecedent seizure history, with two possible aetiologies including SARS-CoV-2 infection and clozapine uptitration. We discuss the presentation, investigations, differential diagnosis and management. In particular, we focus on the electroencephalogram (EEG) findings seen in this case and the electroclinical response to antiepileptic medication. We review the literature and discuss the relevance of this case to the SARS-CoV-2 global pandemic. We emphasise the importance of considering possible neurological manifestations of SARS-CoV-2 infection and highlight seizure disorder as one of the possible presentations. In addition, we discuss the possible effects of clozapine on the electroclinical presentation by way of possible seizure induction as well as discuss the possible EEG changes and we highlight that this needs to be kept in mind especially during rapid titration.
  • |*Betacoronavirus[MESH]
  • |Antipsychotic Agents/*adverse effects[MESH]
  • |COVID-19[MESH]
  • |Clozapine/*adverse effects/therapeutic use[MESH]
  • |Coronavirus Infections/*complications[MESH]
  • |Diagnosis, Differential[MESH]
  • |Electroencephalography/methods[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications[MESH]
  • |Psychotic Disorders/*drug therapy[MESH]
  • |SARS-CoV-2[MESH]


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