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10.1016/j.amjmed.2020.08.043

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33010226!7526639!33010226
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suck abstract from ncbi


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pmid33010226      Am+J+Med 2021 ; 134 (4): 482-489
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  • Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across Europe #MMPMID33010226
  • Sokolski M; Gajewski P; Zymlinski R; Biegus J; Berg JMT; Bor W; Braunschweig F; Caldeira D; Cuculi F; D'Elia E; Edes IF; Garus M; Greenwood JP; Halfwerk FR; Hindricks G; Knuuti J; Kristensen SD; Landmesser U; Lund LH; Lyon A; Mebazaa A; Merkely B; Nawrocka-Millward S; Pinto FJ; Ruschitzka F; Semedo E; Senni M; Sepehri Shamloo A; Sorensen J; Stengaard C; Thiele H; Toggweiler S; Tukiendorf A; Verhorst PM; Wright DJ; Zamorano P; Zuber M; Narula J; Bax JJ; Ponikowski P
  • Am J Med 2021[Apr]; 134 (4): 482-489 PMID33010226show ga
  • PURPOSE: We evaluated whether the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) pandemic was associated with changes in the pattern of acute cardiovascular admissions across European centers. METHODS: We set-up a multicenter, multinational, pan-European observational registry in 15 centers from 12 countries. All consecutive acute admissions to emergency departments and cardiology departments throughout a 1-month period during the COVID-19 outbreak were compared with an equivalent 1-month period in 2019. The acute admissions to cardiology departments were classified into 5 major categories: acute coronary syndrome, acute heart failure, arrhythmia, pulmonary embolism, and other. RESULTS: Data from 54,331 patients were collected and analyzed. Nine centers provided data on acute admissions to emergency departments comprising 50,384 patients: 20,226 in 2020 compared with 30,158 in 2019 (incidence rate ratio [IRR] with 95% confidence interval [95%CI]: 0.66 [0.58-0.76]). The risk of death at the emergency departments was higher in 2020 compared to 2019 (odds ratio [OR] with 95% CI: 4.1 [3.0-5.8], P < 0.0001). All 15 centers provided data on acute cardiology departments admissions: 3007 patients in 2020 and 4452 in 2019; IRR (95% CI): 0.68 (0.64-0.71). In 2020, there were fewer admissions with IRR (95% CI): acute coronary syndrome: 0.68 (0.63-0.73); acute heart failure: 0.65 (0.58-0.74); arrhythmia: 0.66 (0.60-0.72); and other: 0.68(0.62-0.76). We found a relatively higher percentage of pulmonary embolism admissions in 2020: odds ratio (95% CI): 1.5 (1.1-2.1), P?=?0.02. Among patients with acute coronary syndrome, there were fewer admissions with unstable angina: 0.79 (0.66-0.94); non-ST segment elevation myocardial infarction: 0.56 (0.50-0.64); and ST-segment elevation myocardial infarction: 0.78 (0.68-0.89). CONCLUSION: In the European centers during the COVID-19 outbreak, there were fewer acute cardiovascular admissions. Also, fewer patients were admitted to the emergency departments with 4 times higher death risk at the emergency departments.
  • |*COVID-19/epidemiology/prevention & control[MESH]
  • |*Myocardial Ischemia/epidemiology/therapy[MESH]
  • |*Patient Admission/statistics & numerical data/trends[MESH]
  • |Aged[MESH]
  • |Cardiology Service, Hospital/*statistics & numerical data[MESH]
  • |Critical Pathways/*organization & administration[MESH]
  • |Emergency Service, Hospital/*statistics & numerical data[MESH]
  • |Europe/epidemiology[MESH]
  • |Female[MESH]
  • |Hospitalization/statistics & numerical data/trends[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Registries/statistics & numerical data[MESH]


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