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10.1093/cid/ciaa1517

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suck abstract from ncbi


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pmid33009907      Clin+Infect+Dis 2021 ; 73 (11): e4329-e4335
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  • Survival of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Influenza Virus on Human Skin: Importance of Hand Hygiene in Coronavirus Disease 2019 (COVID-19) #MMPMID33009907
  • Hirose R; Ikegaya H; Naito Y; Watanabe N; Yoshida T; Bandou R; Daidoji T; Itoh Y; Nakaya T
  • Clin Infect Dis 2021[Dec]; 73 (11): e4329-e4335 PMID33009907show ga
  • BACKGROUND: The stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on human skin remains unknown, considering the hazards of viral exposure to humans. We generated a model that allows the safe reproduction of clinical studies on the application of pathogens to human skin and elucidated the stability of SARS-CoV-2 on human skin. METHODS: We evaluated the stability of SARS-CoV-2 and influenza A virus (IAV), mixed with culture medium or upper respiratory mucus, on human skin surfaces and the dermal disinfection effectiveness of 80% (weight/weight) ethanol against SARS-CoV-2 and IAV. RESULTS: SARS-CoV-2 and IAV were inactivated more rapidly on skin surfaces than on other surfaces (stainless steel/glass/plastic); the survival time was significantly longer for SARS-CoV-2 than for IAV (9.04 hours [95% confidence interval, 7.96- 10.2 hours] vs 1.82 hours [1.65-2.00 hours]). IAV on other surfaces was inactivated faster in mucus versus medium conditions, while SARS-CoV-2 showed similar stability in the mucus and medium; the survival time was significantly longer for SARS-CoV-2 than for IAV (11.09 hours [10.22-12.00 hours] vs 1.69 hours [1.57-1.81 hours]). Moreover, both SARS-CoV-2 and IAV in the mucus/medium on human skin were completely inactivated within 15 seconds by ethanol treatment. CONCLUSIONS: The 9-hour survival of SARS-CoV-2 on human skin may increase the risk of contact transmission in comparison with IAV, thus accelerating the pandemic. Proper hand hygiene is important to prevent the spread of SARS-CoV-2 infections.
  • |*COVID-19[MESH]
  • |*Hand Hygiene[MESH]
  • |*Influenza A virus[MESH]
  • |*Orthomyxoviridae[MESH]
  • |Humans[MESH]


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