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10.1038/s41598-020-73462-w http://scihub22266oqcxt.onion/10.1038/s41598-020-73462-w 33009451!7532201!33009451     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2020 ; 10 (1): 16412 Nephropedia Template TP {{tp|p=33009451|t=2020. Co-detection of Bordetella pertussis and other respiratory organisms in children hospitalised with lower respiratory tract infection |pdf=|usr=}}{{33009451}} gab.com Text Co-detection of Bordetella pertussis and other respiratory organisms in children hospitalised with lower respiratory tract infection JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33009451 #FOAvip Multiple potential pathogens are frequently co-detected among children with lower respiratory tract infection (LRTI). Evidence indicates that Bordetella pertussis has an important role in the aetiology of LRTI. We aimed to study the association between B. pertussis and other respiratory pathogens in children hospitalised with severe LRTI, and to assess clinical relevance of co-detection. Nasopharyngeal (NP) swabs and induced sputa (IS) were tested with a B. pertussis specific PCR; additionally, IS was tested for other pathogens using a multiplex PCR. We included 454 children, median age 8 months (IQR 4-18), 31 (7%) of whom tested positive for B. pertussis. Children with B. pertussis had more bacterial pathogens detected (3 versus 2; P < 0.001). While B. pertussis showed no association with most pathogens, it was independently associated with Chlamydia pneumoniae, Mycoplasma pneumoniae and parainfluenza viruses with adjusted risk ratios of 4.01 (1.03-15.64), 4.17 (1.42-12.27) and 2.13 (1.03-4.55), respectively. There was a consistent increased risk of severe disease with B. pertussis. Patterns indicated even higher risks when B. pertussis was co-detected with any of the three organisms although not statistically significant. Improving vaccine coverage against B. pertussis would impact not only the incidence of pertussis but also that of severe LRTI generally. Twit Text FOAVip Co-detection of Bordetella pertussis and other respiratory organisms in children hospitalised with lower respiratory tract infection ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33009451 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33009451 #FOAvip English Wikipedia <ref>{{Cite pmid|33009451}}</ref> Co-detection of Bordetella pertussis and other respiratory organisms in children hospitalised with lower respiratory tract infection #MMPMID33009451 Muloiwa R; Dube FS; Nicol MP; Hussey GD; Zar HJ Sci Rep 2020[Oct]; 10 (1): 16412 PMID33009451show ga Multiple potential pathogens are frequently co-detected among children with lower respiratory tract infection (LRTI). Evidence indicates that Bordetella pertussis has an important role in the aetiology of LRTI. We aimed to study the association between B. pertussis and other respiratory pathogens in children hospitalised with severe LRTI, and to assess clinical relevance of co-detection. Nasopharyngeal (NP) swabs and induced sputa (IS) were tested with a B. pertussis specific PCR; additionally, IS was tested for other pathogens using a multiplex PCR. We included 454 children, median age 8 months (IQR 4-18), 31 (7%) of whom tested positive for B. pertussis. Children with B. pertussis had more bacterial pathogens detected (3 versus 2; P < 0.001). While B. pertussis showed no association with most pathogens, it was independently associated with Chlamydia pneumoniae, Mycoplasma pneumoniae and parainfluenza viruses with adjusted risk ratios of 4.01 (1.03-15.64), 4.17 (1.42-12.27) and 2.13 (1.03-4.55), respectively. There was a consistent increased risk of severe disease with B. pertussis. Patterns indicated even higher risks when B. pertussis was co-detected with any of the three organisms although not statistically significant. Improving vaccine coverage against B. pertussis would impact not only the incidence of pertussis but also that of severe LRTI generally. |Bordetella pertussis/genetics/*isolation & purification[MESH] |Chlamydophila pneumoniae/genetics/isolation & purification[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Incidence[MESH] |Infant[MESH] |Male[MESH] |Multiplex Polymerase Chain Reaction/methods[MESH] |Mycoplasma pneumoniae/genetics/isolation & purification[MESH] |Respiratory Tract Infections/*microbiology/*virology[MESH] |Respirovirus/genetics/isolation & purification[MESH] |Sputum/microbiology[MESH]Co-detection of Bordetella pertussis and other respiratory organisms i(epmc).pdf DeepDyve Pubget Overpricing