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10.2807/1560-7917.ES.2020.25.39.2001650 http://scihub22266oqcxt.onion/10.2807/1560-7917.ES.2020.25.39.2001650 33006300!7531073!33006300     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Euro+Surveill 2020 ; 25 (39): ä Nephropedia Template TP {{tp|p=33006300|t=2020. SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene |pdf=|usr=}}{{33006300}} gab.com Text SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene JO: Euro Surveill http://www.kidney.de/pget.php?&tw=1&pmid=33006300 #FOAvip We found that a single nucleotide polymorphism (SNP) in the nucleoprotein gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a patient interfered with detection in a widely used commercial assay. Some 0.2% of the isolates in the EpiCoV database contain this SNP. Although SARS-CoV-2 was still detected by the other probe in the assay, this underlines the necessity of targeting two independent essential regions of a pathogen for reliable detection. Twit Text FOAVip SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene ????Euro Surveill http://www.kidney.de/pget.php?&tw=1&pmid=33006300 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33006300 #FOAvip English Wikipedia <ref>{{Cite pmid|33006300}}</ref> SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene #MMPMID33006300 Ziegler K; Steininger P; Ziegler R; Steinmann J; Korn K; Ensser A Euro Surveill 2020[Oct]; 25 (39): ä PMID33006300show ga We found that a single nucleotide polymorphism (SNP) in the nucleoprotein gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a patient interfered with detection in a widely used commercial assay. Some 0.2% of the isolates in the EpiCoV database contain this SNP. Although SARS-CoV-2 was still detected by the other probe in the assay, this underlines the necessity of targeting two independent essential regions of a pathogen for reliable detection. |*Clinical Laboratory Techniques/methods[MESH] |*Pandemics[MESH] |*Point Mutation[MESH] |*Polymorphism, Single Nucleotide[MESH] |*Real-Time Polymerase Chain Reaction/methods[MESH] |Base Sequence[MESH] |Betacoronavirus/*genetics/isolation & purification[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Contact Tracing[MESH] |Coronavirus Infections/*diagnosis/virology[MESH] |DNA Primers[MESH] |Diagnostic Errors[MESH] |False Negative Reactions[MESH] |Female[MESH] |Genes, Viral[MESH] |Humans[MESH] |Middle Aged[MESH] |Nasopharynx/virology[MESH] |Nucleoproteins/analysis/*genetics[MESH] |Phylogeny[MESH] |Pneumonia, Viral/*diagnosis/virology[MESH] |RNA, Viral/*genetics[MESH] |Romania[MESH] |SARS-CoV-2[MESH] |Travel-Related Illness[MESH]SARS-CoV-2 samples may escape detection because of a single point muta(epmc).pdf DeepDyve Pubget Overpricing