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10.2217/fvl-2020-0163 http://scihub22266oqcxt.onion/10.2217/fvl-2020-0163 33005212!7507811!33005212     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33005212&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Future+Virol 2020 ; 15 (7): 409-417 Nephropedia Template TP {{tp|p=33005212|t=2020. In silico identification of conserved cis-acting RNA elements in the SARS-CoV-2 genome |pdf=|usr=}}{{33005212}} gab.com Text In silico identification of conserved cis-acting RNA elements in the SARS-CoV-2 genome JO: Future Virol http://www.kidney.de/pget.php?&tw=1&pmid=33005212 #FOAvip AIM: The aim of this study was to computationally predict conserved RNA sequences and structures known as cis-acting RNA elements (CREs) in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. MATERIALS & METHODS: Bioinformatics tools were used to analyze and predict CREs by obtaining viral sequences from available databases. RESULTS: Computational analysis revealed the presence of RNA stem-loop structures within the 3' end of the ORF1ab region analogous to previously identified SARS-CoV genomic packaging signals. Alignment-based RNA secondary structure predictions of the 5' end of the SARS-CoV-2 genome also identified conserved CREs. CONCLUSION: These CREs may be potential vaccine and/or antiviral therapeutic targets; however, further studies are warranted to confirm their roles in the SARS-CoV-2 life cycle. Twit Text FOAVip In silico identification of conserved cis-acting RNA elements in the SARS-CoV-2 genome ????Future Virol http://www.kidney.de/pget.php?&tw=1&pmid=33005212 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33005212 #FOAvip English Wikipedia <ref>{{Cite pmid|33005212}}</ref> In silico identification of conserved cis-acting RNA elements in the SARS-CoV-2 genome #MMPMID33005212 Alhatlani BY Future Virol 2020[Jul]; 15 (7): 409-417 PMID33005212show ga AIM: The aim of this study was to computationally predict conserved RNA sequences and structures known as cis-acting RNA elements (CREs) in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. MATERIALS & METHODS: Bioinformatics tools were used to analyze and predict CREs by obtaining viral sequences from available databases. RESULTS: Computational analysis revealed the presence of RNA stem-loop structures within the 3' end of the ORF1ab region analogous to previously identified SARS-CoV genomic packaging signals. Alignment-based RNA secondary structure predictions of the 5' end of the SARS-CoV-2 genome also identified conserved CREs. CONCLUSION: These CREs may be potential vaccine and/or antiviral therapeutic targets; however, further studies are warranted to confirm their roles in the SARS-CoV-2 life cycle. äIn silico identification of conserved cis-acting RNA elements in the S(epmc).pdf DeepDyve Pubget Overpricing