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10.1364/OL.402897 http://scihub22266oqcxt.onion/10.1364/OL.402897 33001920!ä!33001920 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Opt+Lett 2020 ; 45 (19): 5428-5431 Nephropedia Template TP {{tp|p=33001920|t=2020. Light and corona: guided-wave readout for coronavirus spike protein-host-receptor binding |pdf=|usr=}}{{33001920}} gab.com Text Light and corona: guided-wave readout for coronavirus spike protein-host-receptor binding JO: Opt Lett http://www.kidney.de/pget.php?&tw=1&pmid=33001920 #FOAvip We show that waveguide sensors can enable a quantitative characterization of coronavirus spike glycoprotein-host-receptor binding-the process whereby coronaviruses enter human cells, causing disease. We demonstrate that such sensors can help quantify and eventually understand kinetic and thermodynamic properties of viruses that control their affinity to targeted cells, which is known to significantly vary in the course of virus evolution, e.g., from SARS-CoV to SARS-CoV-2, making the development of virus-specific drugs and vaccine difficult. With the binding rate constants and thermodynamic parameters as suggested by the latest SARS-CoV-2 research, optical sensors of SARS-CoV-2 spike protein-receptor binding may be within sight. Twit Text FOAVip Light and corona: guided-wave readout for coronavirus spike protein-host-receptor binding ????Opt Lett http://www.kidney.de/pget.php?&tw=1&pmid=33001920 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33001920 #FOAvip English Wikipedia <ref>{{Cite pmid|33001920}}</ref> Light and corona: guided-wave readout for coronavirus spike protein-host-receptor binding #MMPMID33001920 Fedotov IV; Yi Z; Voronin AA; Svidzinsky AA; Sower K; Liu X; Vlasova E; Peng T; Liu X; Moiseev SA; Belousov VV; Sokolov AV; Scully MO; Zheltikov AM Opt Lett 2020[Oct]; 45 (19): 5428-5431 PMID33001920show ga We show that waveguide sensors can enable a quantitative characterization of coronavirus spike glycoprotein-host-receptor binding-the process whereby coronaviruses enter human cells, causing disease. We demonstrate that such sensors can help quantify and eventually understand kinetic and thermodynamic properties of viruses that control their affinity to targeted cells, which is known to significantly vary in the course of virus evolution, e.g., from SARS-CoV to SARS-CoV-2, making the development of virus-specific drugs and vaccine difficult. With the binding rate constants and thermodynamic parameters as suggested by the latest SARS-CoV-2 research, optical sensors of SARS-CoV-2 spike protein-receptor binding may be within sight. |*Betacoronavirus[MESH] |*Biosensing Techniques[MESH] |*Coronavirus Infections[MESH] |*Pandemics[MESH] |*Pneumonia, Viral[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Binding Sites[MESH] |COVID-19[MESH] |Humans[MESH] |Optics and Photonics/*instrumentation[MESH] |Peptidyl-Dipeptidase A/*metabolism[MESH] |Protein Binding/physiology[MESH] |Receptors, Virus/*metabolism[MESH] |SARS-CoV-2[MESH]Light and corona: guided-wave readout for coronavirus spike protein-ho(epmc).pdf DeepDyve Pubget Overpricing