An ace model for SARS-CoV-2 infection #MMPMID33000129
Major J; Wack A
J Exp Med 2020[Dec]; 217 (12): ä PMID33000129show ga
Developing effective in vivo models for SARS-CoV-2 infection is crucial for mechanistic studies of COVID-19 disease progression. In this issue of JEM, Israelow et al. (https://doi.org/10.1084/jem.20201241) generate a model that supports SARS-CoV-2 infection in mice, which they use to characterize type I IFN-driven pulmonary inflammation.