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pmid33000108      Ann+Acad+Med+Singap 2020 ; 49 (7): 456-461
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  • Chest Radiography in Coronavirus Disease 2019 (COVID-19): Correlation with Clinical Course #MMPMID33000108
  • Zhou JC; Hui TC; Tan CH; Khoo HW; Young BE; Lye DC; Lee YS; Kaw GJ
  • Ann Acad Med Singap 2020[Jul]; 49 (7): 456-461 PMID33000108show ga
  • Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 and was declared a global pandemic by the World Health Organization on 11 March 2020. A definitive diagnosis of COVID-19 is made after a positive result is obtained on reverse transcription-polymerase chain reaction assay. In Singapore, rigorous contact tracing was practised to contain the spread of the virus. Nasal swabs and chest radiographs (CXR) were also taken from individuals who were suspected to be infected by COVID-19 upon their arrival at a centralised screening centre. From our experience, about 40% of patients who tested positive for COVID-19 had initial CXR that appeared "normal". In this case series, we described the temporal evolution of COVID-19 in patients with an initial "normal" CXR. Since CXR has limited sensitivity and specificity in COVID-19, it is not suitable as a first-line diagnostic tool. However, when CXR changes become unequivocally abnormal, close monitoring is recommended to manage potentially severe COVID-19 pneumonia.
  • |*Betacoronavirus[MESH]
  • |*Clinical Laboratory Techniques[MESH]
  • |Adult[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Coronavirus Infections/*complications/diagnosis/*diagnostic imaging[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/*diagnostic imaging[MESH]
  • |Radiography[MESH]
  • |SARS-CoV-2[MESH]


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