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10.23736/S0026-4806.20.06952-9

http://scihub22266oqcxt.onion/10.23736/S0026-4806.20.06952-9
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32996727!ä!32996727

suck abstract from ncbi


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pmid32996727      Minerva+Med 2022 ; 113 (2): 281-290
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  • Continuous positive airway pressure and pronation outside the Intensive Care Unit in COVID-19 acute respiratory distress syndrome #MMPMID32996727
  • Ramirez GA; Bozzolo EP; Castelli E; Marinosci A; Angelillo P; Damanti S; Scotti R; Gobbi A; Centurioni C; DI Scala F; Morgillo A; Castagna A; Conte C; Assanelli A; DE Cobelli F; Calcaterra B; Cabrini L; Carco F; Turi S; Silvani P; Dagna L; Zangrillo A; Landoni G; Tresoldi M
  • Minerva Med 2022[Apr]; 113 (2): 281-290 PMID32996727show ga
  • BACKGROUND: The efficacy and safety of continuous positive airway pressure and respiratory physiotherapy outside the Intensive Care Unit during a pandemic. METHODS: In this cohort study performed in February-May 2020 in a large teaching hospital in Milan, COVID-19 patients with adult respiratory distress syndrome receiving continuous positive airway pressure (positive end-expiratory pressure =10 cm H2O, FiO2=0.6, daily treatment duration: 4x3h-cycles) and respiratory physiotherapy including pronation outside the Intensive Care Unit were followed-up. RESULTS: Of 90 acute respiratory distress syndrome (ARDS) patients treated with continuous positive airway pressure (45/90, 50% pronated at least once) outside the Intensive Care Unit and with a median (interquartile) follow-up of 37 (11-46) days, 45 (50%) were discharged at home, 28 (31%) were still hospitalized, and 17 (19%) died. Continuous positive airway pressure failure was recorded for 35 (39%) patients. Patient mobilization was associated with reduced failure rates (P=0.033). No safety issues were observed. CONCLUSIONS: Continuous positive airway pressure with patient mobilization (including pronation) was effective and safe in patients with ARDS due to COVID-19 managed outside the Intensive Care Unit setting during the pandemic.
  • |*COVID-19/complications/therapy[MESH]
  • |*Respiratory Distress Syndrome/therapy[MESH]
  • |Adult[MESH]
  • |Cohort Studies[MESH]
  • |Continuous Positive Airway Pressure[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]


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