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10.1016/j.rmcr.2020.101221 http://scihub22266oqcxt.onion/10.1016/j.rmcr.2020.101221 32995261!7502379!32995261     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Respir+Med+Case+Rep 2020 ; 31 (ä): 101221 Nephropedia Template TP {{tp|p=32995261|t=2020. Methylprednisolone pulse therapy: An alternative management of severe COVID-19 |pdf=|usr=}}{{32995261}} gab.com Text Methylprednisolone pulse therapy: An alternative management of severe COVID-19 JO: Respir Med Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=32995261 #FOAvip We present two cases of severe COVID-19 that were rejected by medical institutions. The management of the disease was done at home with methylprednisolone (MP) pulse therapy for three days. This resulted in a favorable evolution and resolution of most symptoms. COVID-19 infection presents as asymptomatic disease, non-severe symptomatic disease, and severe respiratory inflammatory disease. The first two forms are dependent on viral response and a "cytokine storm" is responsible for the progression into severe disease. Glucocorticoids (GC) reduce inflammation by different mechanism depending of their concentration. Pulses lead to overall apoptosis of immune cells. Studies using pulse MP as treatment for SARS-CoV-1 showed clinical improvement and decreased incidence of ARDS compared with patients who received low dose steroid treatment. Inhibition of excessive inflammation through timely administration of GC in the early stage of inflammatory cytokine storm effectively prevents the occurrence of ARDS. Twit Text FOAVip Methylprednisolone pulse therapy: An alternative management of severe COVID-19 ????Respir Med Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=32995261 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32995261 #FOAvip English Wikipedia <ref>{{Cite pmid|32995261}}</ref> Methylprednisolone pulse therapy: An alternative management of severe COVID-19 #MMPMID32995261 Saune PM; Bryce-Alberti M; Portmann-Baracco AS; Accinelli RA Respir Med Case Rep 2020[]; 31 (ä): 101221 PMID32995261show ga We present two cases of severe COVID-19 that were rejected by medical institutions. The management of the disease was done at home with methylprednisolone (MP) pulse therapy for three days. This resulted in a favorable evolution and resolution of most symptoms. COVID-19 infection presents as asymptomatic disease, non-severe symptomatic disease, and severe respiratory inflammatory disease. The first two forms are dependent on viral response and a "cytokine storm" is responsible for the progression into severe disease. Glucocorticoids (GC) reduce inflammation by different mechanism depending of their concentration. Pulses lead to overall apoptosis of immune cells. Studies using pulse MP as treatment for SARS-CoV-1 showed clinical improvement and decreased incidence of ARDS compared with patients who received low dose steroid treatment. Inhibition of excessive inflammation through timely administration of GC in the early stage of inflammatory cytokine storm effectively prevents the occurrence of ARDS. äMethylprednisolone pulse therapy: An alternative management of severe (epmc).pdf DeepDyve Pubget Overpricing