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10.3390/nu12102957 http://scihub22266oqcxt.onion/10.3390/nu12102957 32992541!7601906!32992541     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nutrients 2020 ; 12 (10): ä Nephropedia Template TP {{tp|p=32992541|t=2020. Nutrition Mediates the Relationship between Osteosarcopenia and Frailty: A Pathway Analysis |pdf=|usr=}}{{32992541}} gab.com Text Nutrition Mediates the Relationship between Osteosarcopenia and Frailty: A Pathway Analysis JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=32992541 #FOAvip Osteosarcopenia is associated with increased risk of adverse outcomes such as falls and fractures. Its association with frailty is less well-described, particularly in independent community-dwelling older adults. Although nutrition plays a crucial role in maintaining bone and muscle health, the complex relationship between osteosarcopenia and nutrition in the pathogenesis of frailty remains to be elucidated. In this cross-sectional analysis of 230 independent, community-dwelling individuals (mean age 67.2 +/- 7.4 years), we examined the associations between osteosarcopenia with nutritional status and frailty, and the mediating role of nutrition in the association between osteosarcopenia and frailty. Osteosarcopenia was defined as fulfilling both the Asian Working Group for Sarcopenia 2019 consensus definition (low relative appendicular skeletal muscle mass adjusted for height, in the presence of either of either low handgrip strength or slow gait speed) and T-score </= -2.5 SD on bone mineral densitometry. We assessed frailty using the modified Fried criteria and nutrition using the Mini-Nutritional Assessment. We performed multiple linear regression, followed by pathway analysis to ascertain whether nutrition mediates the relationship between osteosarcopenia and frailty. Our study population comprised: 27 (11.7%) osteosarcopenic, 35 (15.2%) sarcopenic, 36 (15.7%) osteoporotic and 132 (57.4%) normal (neither osteosarcopenic, sarcopenic nor osteoporotic). Osteosarcopenia (beta = 1.1, 95% CI 0.86-1.4) and sarcopenia (beta = 1.1, 95% CI 0.90-1.4) were significantly associated with frailty, but not osteoporosis. Nutrition mediated the association between osteosarcopenia and frailty (indirect effect estimate 0.09, bootstrap 95% CI 0.01-0.22). In conclusion, osteosarcopenia is associated with frailty and poorer nutritional status, with nutrition mediating the association between osteosarcopenia and frailty. Our findings support early nutritional assessment and intervention in osteosarcopenia to mitigate the risk of frailty. Twit Text FOAVip Nutrition Mediates the Relationship between Osteosarcopenia and Frailty: A Pathway Analysis ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=32992541 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32992541 #FOAvip English Wikipedia <ref>{{Cite pmid|32992541}}</ref> Nutrition Mediates the Relationship between Osteosarcopenia and Frailty: A Pathway Analysis #MMPMID32992541 Chew J; Yeo A; Yew S; Tan CN; Lim JP; Hafizah Ismail N; Lim WS Nutrients 2020[Sep]; 12 (10): ä PMID32992541show ga Osteosarcopenia is associated with increased risk of adverse outcomes such as falls and fractures. Its association with frailty is less well-described, particularly in independent community-dwelling older adults. Although nutrition plays a crucial role in maintaining bone and muscle health, the complex relationship between osteosarcopenia and nutrition in the pathogenesis of frailty remains to be elucidated. In this cross-sectional analysis of 230 independent, community-dwelling individuals (mean age 67.2 +/- 7.4 years), we examined the associations between osteosarcopenia with nutritional status and frailty, and the mediating role of nutrition in the association between osteosarcopenia and frailty. Osteosarcopenia was defined as fulfilling both the Asian Working Group for Sarcopenia 2019 consensus definition (low relative appendicular skeletal muscle mass adjusted for height, in the presence of either of either low handgrip strength or slow gait speed) and T-score |*Nutritional Status[MESH] |Accidental Falls[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Cross-Sectional Studies[MESH] |Female[MESH] |Fractures, Bone/etiology[MESH] |Frailty/*complications[MESH] |Hand Strength[MESH] |Humans[MESH] |Independent Living[MESH] |Male[MESH] |Middle Aged[MESH] |Osteoporosis/*complications/epidemiology[MESH]Nutrition Mediates the Relationship between Osteosarcopenia and Frailt(epmc).pdf DeepDyve Pubget Overpricing