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10.1159/000511738

http://scihub22266oqcxt.onion/10.1159/000511738
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32992323!7573914!32992323
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suck abstract from ncbi


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pmid32992323      Obes+Facts 2020 ; 13 (5): 528-533
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  • A Time Frame for Testing Negative for SARS-COV2 in People with Obesity #MMPMID32992323
  • Dicker D; Lev S; Gottesman T; Kournos T; Dotan M; Ashorov N; Marcoviciu D; Golan R
  • Obes Facts 2020[]; 13 (5): 528-533 PMID32992323show ga
  • OBJECTIVE: Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of symptomatic patients. METHODS: We followed 34 patients with laboratory-confirmed COVID-19 infection who recovered fromthe infection. All diagnoses were given using semi-quantitative RT-PCR on nasopharyngeal swabs. Envelope protein gene (E), RNA-dependent RNA polymerase gene (RdRP), and nucleocapsid gene (N) were measured by RT-PCR. Weight was measured and height was self-reported. RESULTS: Mean +/- SD age was 51.8 +/- 16.7 years. Mean +/- SD body mass index (BMI) was 27.4 +/- 4.7 kg/m2. 26% (9/34) had obesity, with BMI above 30 kg/m2. Fifteen patients had BMI between 25 and 29.9 kg/m2. The mean length of hospital stay was longer for those with a BMI >25 kg/m2 (n = 24) than for those with a normal BMI (19.2 vs. 16.0 days, p = 0.08). Comparing people with obesity (BMI >30 kg/m2 or above) to those without obesity, the difference was larger (20.6 vs. 16.0 days, p = 0.06). A trend for correlation between body weight and the time to negative detection of RdRp gene was found (r = 0.33, p = 0.09). CONCLUSIONS: Our results highlight the need for priority of early detection and testing, and early therapy for people with obesity and COVID-19 infections.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Betacoronavirus[MESH]
  • |Body Mass Index[MESH]
  • |Body Weight[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Coronavirus Infections/*diagnosis[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Length of Stay[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Obesity/*complications/virology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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