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10.1016/j.jhin.2020.09.026

http://scihub22266oqcxt.onion/10.1016/j.jhin.2020.09.026
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32991941!7521917!32991941
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suck abstract from ncbi


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pmid32991941      J+Hosp+Infect 2021 ; 107 (ä): 45-49
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  • Ethanol and isopropanol inactivation of human coronavirus on hard surfaces #MMPMID32991941
  • Meyers C; Kass R; Goldenberg D; Milici J; Alam S; Robison R
  • J Hosp Infect 2021[Jan]; 107 (ä): 45-49 PMID32991941show ga
  • BACKGROUND: The coronavirus disease 2019 pandemic has greatly increased the frequency of disinfecting surfaces in public places, causing a strain on the ability to obtain disinfectant solutions. An alternative is to use plain alcohols (EtOH and IPA) or sodium hypochlorite (SH). AIM: To determine the efficacy of various concentrations of EtOH, IPA and SH on a human coronavirus (HCoV) dried on to surfaces using short contact times. METHODS: High concentrations of infectious HCoV were dried on to porcelain and ceramic tiles, then treated with various concentrations of the alcohols for contact times of 15 s, 30 s and 1 min. Three concentrations of SH were also tested. Reductions in titres were measured using the tissue culture infectious dose 50 assay. FINDINGS: Concentrations of EtOH and IPA from 62% to 80% were very efficient at inactivating high concentrations of HCoV dried on to tile surfaces, even with a 15-s contact time. Concentrations of 95% dehydrated the virus, allowing infectious virus to survive. The dilutions of SH recommended by the Centers for Disease Control and Prevention (1/10 and 1/50) were efficient at inactivating high concentrations of HCoV dried on to tile surfaces, whereas a 1/100 dilution had substantially lower activity. CONCLUSIONS: Multiple concentrations of EtOH, IPA and SH efficiently inactivated infectious HCoV on hard surfaces, typical of those found in public places. Often no remaining infectious HCoV could be detected.
  • |2-Propanol/*pharmacology[MESH]
  • |Ceramics[MESH]
  • |Dental Porcelain[MESH]
  • |Disinfectants/chemistry/*pharmacology[MESH]
  • |Ethanol/*pharmacology[MESH]
  • |SARS-CoV-2/*drug effects[MESH]
  • |Sodium Hypochlorite/pharmacology[MESH]
  • |Surface Properties[MESH]


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