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10.1532/hsf.3077 http://scihub22266oqcxt.onion/10.1532/hsf.3077 32990580!ä!32990580 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Heart+Surg+Forum 2020 ; 23 (5): E574-E578 Nephropedia Template TP {{tp|p=32990580|t=2020. The Effect of Atrial Septal Defect in the Treatment of ARDS with Left Ventricular Dysfunction Simulating Severe COVID-19 |pdf=|usr=}}{{32990580}} gab.com Text The Effect of Atrial Septal Defect in the Treatment of ARDS with Left Ventricular Dysfunction Simulating Severe COVID-19 JO: Heart Surg Forum http://www.kidney.de/pget.php?&tw=1&pmid=32990580 #FOAvip OBJECTIVE: To explore the effect of atrial septal defect (ASD) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) in the treatment of ARDS combined with left ventricular dysfunction (LVD) to find a new effective method for treating severe COVID-19 patients. MATERIALS AND METHODS: Five large animal ARDS models of sheep were established by intravenous injection of Lipopolysaccharide. ASD was made under general anesthesia and VA-ECMO was simulated by extracorporeal circulation machine. The oxygenation of peripheral blood, systemic circulation, and cardiac function were observed under conditions of closed and opened ASD, and the significance of ASD shunt in improving cardiopulmonary function was evaluated. RESULTS: With ASD closed, the atrial shunts disappeared, the peripheral artery pressure of oxygen(PaO2): 141.2+/-21.4mmHg, the oxygenation index (PaO2/FiO2): 353.0+/-53.5, the mean blood pressure (MAP): 49.3+/-13.5 mmHg, the heart was full; with ASD opened, the left-to-right shunt was observed, PaO2: 169.3+/-18.9mmHg, PaO2/FiO2: 423.3+/-47.3, MAP: 68.2+/-16.1 mmHg, the range of cardiac motion significantly increased, heart beat was powerful, and systemic circulation significantly improved. Statistical analysis showed that there were significant differences between opened and closed ASD (P < .01). CONCLUSION: ASD plus VA-ECMO is an effective method for the treatment of ARDS combined with LVD, which is the main cause of death in severe COVID-19 patients. However, further clinical validation is needed. Twit Text FOAVip The Effect of Atrial Septal Defect in the Treatment of ARDS with Left Ventricular Dysfunction Simulating Severe COVID-19 ????Heart Surg Forum http://www.kidney.de/pget.php?&tw=1&pmid=32990580 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32990580 #FOAvip English Wikipedia <ref>{{Cite pmid|32990580}}</ref> The Effect of Atrial Septal Defect in the Treatment of ARDS with Left Ventricular Dysfunction Simulating Severe COVID-19 #MMPMID32990580 Diao L; Yang Y; Zhang B; Shi Q; Fan H; Liu J; Li Y; Wu B; Wu Y; Qiu H; Li W Heart Surg Forum 2020[Aug]; 23 (5): E574-E578 PMID32990580show ga OBJECTIVE: To explore the effect of atrial septal defect (ASD) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) in the treatment of ARDS combined with left ventricular dysfunction (LVD) to find a new effective method for treating severe COVID-19 patients. MATERIALS AND METHODS: Five large animal ARDS models of sheep were established by intravenous injection of Lipopolysaccharide. ASD was made under general anesthesia and VA-ECMO was simulated by extracorporeal circulation machine. The oxygenation of peripheral blood, systemic circulation, and cardiac function were observed under conditions of closed and opened ASD, and the significance of ASD shunt in improving cardiopulmonary function was evaluated. RESULTS: With ASD closed, the atrial shunts disappeared, the peripheral artery pressure of oxygen(PaO2): 141.2+/-21.4mmHg, the oxygenation index (PaO2/FiO2): 353.0+/-53.5, the mean blood pressure (MAP): 49.3+/-13.5 mmHg, the heart was full; with ASD opened, the left-to-right shunt was observed, PaO2: 169.3+/-18.9mmHg, PaO2/FiO2: 423.3+/-47.3, MAP: 68.2+/-16.1 mmHg, the range of cardiac motion significantly increased, heart beat was powerful, and systemic circulation significantly improved. Statistical analysis showed that there were significant differences between opened and closed ASD (P < .01). CONCLUSION: ASD plus VA-ECMO is an effective method for the treatment of ARDS combined with LVD, which is the main cause of death in severe COVID-19 patients. However, further clinical validation is needed. |*Betacoronavirus[MESH] |*Extracorporeal Membrane Oxygenation[MESH] |Animals[MESH] |COVID-19[MESH] |Coronavirus Infections/*complications[MESH] |Diagnosis, Differential[MESH] |Disease Models, Animal[MESH] |Heart Septal Defects, Atrial/*complications[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications[MESH] |Respiratory Distress Syndrome/etiology/*therapy[MESH] |SARS-CoV-2[MESH] |Sheep[MESH]The Effect of Atrial Septal Defect in the Treatment of ARDS with Left (epmc).pdf DeepDyve Pubget Overpricing