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10.1016/j.vaccine.2020.09.041

http://scihub22266oqcxt.onion/10.1016/j.vaccine.2020.09.041
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suck abstract from ncbi


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pmid32988688      Vaccine 2020 ; 38 (45): 7002-7006
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  • Intention to participate in a COVID-19 vaccine clinical trial and to get vaccinated against COVID-19 in France during the pandemic #MMPMID32988688
  • Detoc M; Bruel S; Frappe P; Tardy B; Botelho-Nevers E; Gagneux-Brunon A
  • Vaccine 2020[Oct]; 38 (45): 7002-7006 PMID32988688show ga
  • INTRODUCTION: The world is facing the COVID-19 pandemic. The development of a vaccine is challenging. We aimed to determine the proportion of people who intend to get vaccinated against COVID-19 in France or to participate in a vaccine clinical trial. METHODS: We conducted an anonymous on-line survey from the 26th of March to the 20th of April 2020. Primary endpoints were the intention to get vaccinated against COVID-19 if a vaccine was available or participate in a vaccine clinical trial. RESULTS: Three thousand two hundred and fifty nine individuals answered the survey; women accounted for 67.4% of the respondents. According to their statements, 2.512 participants (77.6%, 95% CI 76.2-79%) will certainly or probably agree to get vaccinated against COVID-19. Older age, male gender, fear about COVID-19, being a healthcare worker and individual perceived risk were associated with COVID-19 vaccine acceptance. Vaccine hesitancy was associated with a decrease in COVID-19 vaccine acceptance. One thousand and five hundred and fifty respondents (47.6% 95% CI 45.9-49.3%) will certainly or probably agree to participate in a COVID-19 vaccine clinical trial. Older age, male gender, being a healthcare worker and individual perceived risk were associated with potential acceptance to participate in a COVID-19 vaccine clinical trial. Vaccine hesitancy was associated with refusal for participation in a COVID-19 vaccine clinical trial. CONCLUSIONS: Nearly 75% and 48% of the survey respondents were respectively likely to accept vaccination or participation in a clinical trial against COVID-19. Vaccine hesitancy will be the major barrier to COVID-19 vaccine uptake.
  • |Adult[MESH]
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus/pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus Infections/epidemiology/immunology/*prevention & control/*psychology[MESH]
  • |Female[MESH]
  • |France/epidemiology[MESH]
  • |Health Personnel[MESH]
  • |Humans[MESH]
  • |Intention[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Patient Acceptance of Health Care/*psychology[MESH]
  • |Patient Safety[MESH]
  • |Pneumonia, Viral/epidemiology/immunology/*prevention & control/*psychology[MESH]
  • |SARS-CoV-2[MESH]
  • |Sex Factors[MESH]
  • |Surveys and Questionnaires[MESH]
  • |Vaccination/*psychology[MESH]


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